新型杯冠衍生物的合成研究  

Synthesis of novel calix [4] crown derivatives

作　　者：蒋忠良[1] 常维夫[1] 段辉[1] 

机构地区：[1]同济大学化学系,上海200092

出　　处：《精细与专用化学品》2013年第2期46-47,共2页Fine and Specialty Chemicals

摘　　要：本文从对叔丁基杯[4]芳烃出发,对其下沿的酚羟基进行修饰,先后在1-和3-酚羟基位点引入乙基和苄基。最后在NaH/THF中与四甘醇二对甲苯磺酸酯反应得到目标化合物杯冠衍生物。所合成化合物结构经1HNMR和MS表征。Using p-tert-butylcalix [ 4 ] arene as starting materials, a novel calix [ 4 ~ crown derivatives have been synthesized by introducing branched ethyl and benzyl at 1-and 3-posions of phenolic hydroxyl groups, followed by the re- action of compound with tetraethylene glycol ditosylate in NaH/THF solution. The structure of synthetic compounds was confirmed by ^1HNMR and MS.

关 键 词：杯冠 四甘醇二对甲苯磺酸酯 合成 

分 类 号：O621.3[理学—有机化学]