谱域光学相干层析系统轴向分辨率提高方法  

Method to Improve Axial Resolution of Spectral Domain Optical Coherence Tomography

作　　者：崇博[1] 朱永凯[1] 

机构地区：[1]南京航空航天大学自动化学院,江苏南京210016

出　　处：《光学学报》2013年第2期151-156,共6页Acta Optica Sinica

基　　金：江苏省科技支撑计划项目(BE2012752);南京航空航天大学基本科研业务费专项科研项目(NS2011017);航空科学基金(2011ZD52049)资助课题

摘　　要：在谱域光学相干层析成像系统中,宽带光源的群速度色散会降低系统的轴向分辨率,导致成像分辨率和对比度的下降。分析了色散对谱域光学相干层析成像系统轴向分辨率的影响,提出了一种基于光谱校正的轴向分辨率提高方法,通过三步阈值迭代进行光谱坐标的二阶系数拟合,得到校正后的光谱数据并进行深度位置信息解调。以单层薄玻璃片和西红柿表皮组织为测量样品进行了谱域光学相干层析成像实验,结果表明,该方法与现有方法相比,能够有效补偿色散对系统轴向分辨率的影响,可将轴向分辨率有效提高10μm,得到分辨率更高的二维扫描层析图像,该方法对于不同测量样品具有普遍适用性。In spectral domain optical coherence tomographic system, group velocity dispersion of broadband light source reduces axial resolution and leads to the decrease of image resolution and contrast. The decline of axial resolution of spectral domain optical coherence tomography （SD-OCT） caused by dispersion is analyzed and a method based on spectrum correction to improve axial resolution of spectral domain optical coherence tomography is proposed. Spectrum coordinate is processed by second-order coefficients fitting. The coefficients are got by three- step threshold iteration. The axial depth is demodulated by the corrected spectrum. Spectral-domain optical coherence tomography experiments of single-layer thin glass and tomato epidermis tissue show that, compared with traditional method, the axial resolution is improved more than 10 μm and resolution of the two-dimensional tomogram is higher. It is generally applicative for different samples.

关 键 词：医用光学 生物光学 谱域光学相干层析成像 宽带光源 群速度色散 轴向分辨率 光谱校正 

分 类 号：TN247[电子电信—物理电子学]