一种植物复方消毒剂对金黄色葡萄球菌杀灭效果的研究  

STUDY ON GERMICIDAL EFFICACY OF A COMPOUND HERBAL DISINFECTANT OF Staphylococcus aureus

作　　者：王莎莎[1] 邱真真[1] 鲁晓晴[1] 

机构地区：[1]青岛大学医学院公共卫生学系,山东青岛266071

出　　处：《中国消毒学杂志》2013年第1期1-3,共3页Chinese Journal of Disinfection

基　　金：青岛市科技局资助项目(10-3-3-1-7-nsh)

摘　　要：目的研究一种植物复方消毒剂对金黄色葡萄球菌的杀灭效果。方法采用悬液定量杀菌试验方法,对其杀菌效果及相关性能进行了实验室观察。结果该复方消毒剂含穿心莲、金银花、板蓝根提取物均为1 000 mg/L与20 g/L壳聚糖,为液体制剂。用该复方消毒剂原液对悬液内金黄色葡萄球菌作用5 min,平均杀灭对数值为5.0。菌悬液内含25%小牛血清可使该复方消毒剂杀菌效果明显下降;消毒液pH值变化明显影响其杀菌效果。将该复方消毒剂密封储存于54℃恒温箱14 d后,其对金黄色葡萄球菌杀灭对数值下降为1.25。结论该植物复方消毒剂对金黄色葡萄球菌具有良好杀灭效果,但有机物、pH值变化对其杀菌效果有不良影响,储存性能不稳定。Objective To study the germicidal efficacy of a compound herbal disinfectant ofStaphylococcus aureus. Methods The suspension quantitative germicidal test was used to test the germicidal efficacy and related properties of the disinfectant in the laboratory. Results The compound disinfectant solution contains 1 000 mg/L extract of Common An- drographis Herb, Honeysuckle Flower, Indigowoad Root respectively, and 20 g/L chitosan. The killing logarithm value （KL） of S. aureus in suspension exposed to the compound disinfectant for 5 min was 5. 0. The germicidal efficacy of the compound disinfectant was obviously influenced when the bacteria suspension contained 25% calf serum, and when pH val- ue of the disinfectant changed. When the compound disinfectant was stored in 54℃incubator for 14 days, KL of S. aureus decreased to 1.25. Conclusion The compound herbal disinfectant has good germicidal efficacy on S. aureus. However, the germicidal efficacy is influenced by organic matters, pH value and long- term storage.

关 键 词：植物消毒剂 复方 壳聚糖 金黄色葡萄球菌 杀菌效果 

分 类 号：R187[医药卫生—流行病学]