彩色多普勒超声检测颈动脉粥样硬化与脑梗死的相关研究  

Correlative Study on Intima-Media Thickness of Carotid Artery in Cerebral Infarction by Colour Doppler Ultrasound

作　　者：赵康仁[1] 任乃勇[1] 张渭芳[1] 靳彪[1] 钱进军[1] 

机构地区：[1]江苏大学第四附属医院神经内科,江苏镇江212001

出　　处：《临床医学工程》2013年第2期129-131,共3页Clinical Medicine & Engineering

基　　金：镇江市社会发展科技支撑项目(SH2010021)

摘　　要：目的通过彩色多普勒超声检测脑梗死患者的颈动脉内-中膜的厚度,探讨引起颈动脉粥样硬化的危险因素,研究颈动脉粥样硬化与脑梗死的关系。方法用彩色多普勒超声检测了113例脑梗死患者的颈动脉超声特征,了解其颈动脉内-中膜厚度及其斑块性质,同时与107例体检者做对照。结果脑梗死患者的颈动脉粥样硬化的发生率明显高于对照组,两者比较有显著性差异(P<0.01)。分析发现患者的年龄、糖尿病、高血压与颈动脉斑块的发生率有显著相关性(P<0.01)。血纤维蛋白原水平及血脂水平与颈动脉斑块形成密切相关(P<0.05)。脑梗死组与对照组在性别、吸烟、饮酒方面间差异无统计学意义。脑梗死患者颈动脉斑块的发生率明显增加(P<0.01)。结论颈动脉内-中膜厚度与脑梗死的发生有明显的相关性,颈动脉的内-中膜增厚与斑块形成是许多因素相互作用的结果,颈动脉粥样硬化是引起脑梗死非常重要的危险因素。Objective To examine the intima-media thickness of carotid artery in cerebral infarction by colour Doppler ultrasound, and investigate the risk factors of the carotid artery atherosclerosis and the relation to carotid atherosclerosis with cerebral infarction. Methods Using the colour doppler ultrasonic technique, the carotid intima-medial thickness, plaques were measured in 113 cases of cerebral infarction, and compared with 107 cases in the control group. Results Patients with cerebral infarction had significantly higher incidence of carotid arteriosclerosis than the control group, with significant difference （P 〈0.01）. Carotid plaque increased progressively with age, diabetes, high blood pressure （P〈0.01）. It was correlated to blood fibrinogen level and blood lipid level（P〈0.05）. The two groups had no statistical difference in gender, smoking and drinking. The incidence of carotid plaque in cerebral infarction group was significantly higher （P 〈0.01） Conclusions Cerebral infarction occurrence is closely associated with cerebral infarction; the intima-media thickness of carotid artery and plaques are the result of the interaction of many factors, carotid atherosclerosis is an important risk factor for cerebral infarction.

关 键 词：颈动脉粥样硬化 彩色多普勒超声 脑梗死 

分 类 号：R445.1[医药卫生—影像医学与核医学]