2008-2011年贵州省手足口病报告病例流行病学特征分析  

Analysis on Epidemiological Characteristics of Hand,Foot and Mouth Disease in Guizhou Province from 2008 to 2011

作　　者：李雷雷[1] 隋霞[2] 周敬祝[3] 庄妍[3] 黄艳[3] 唐光鹏[3] 金连梅[1] 王定明[3] 冯子健[1] 

机构地区：[1]中国疾病预防控制中心,北京102206 [2]卫生部医院管理研究所 [3]贵州省疾病预防控制中心

出　　处：《实用预防医学》2013年第2期165-167,共3页Practical Preventive Medicine

摘　　要：目的了解2008-2011年贵州省手足口病流行特点和规律,为手足口病的防控工作提供参考依据。方法利用疾病监测信息系统收集2008-2011年贵州省手足口病病例数据,描述其三间分布情况。结果 2008-2011年,贵州省共报告手足口病病例73 918例,报告重症病例1 127例,其中死亡69人。2008-2010年贵州省手足口病发病呈单峰形式,而2011年呈双峰,第二个高峰为47～49周。以婴幼儿、学生为主,男女比例为1.7:1,5岁以下儿童病例占89%。发病率较高的地区主要包括贵阳市、遵义市、安顺市及六盘水市。报告实验室诊断病例2 218例(占总病例数的3%),病原体以EV71阳性为主(占49%)。结论贵州省手足口病流行强度逐年增强,5岁以下儿童是发病主要人群,重症与死亡病例较往年有较大增加,EV71是引起重症与死亡的主要病原体。Objective To investigate the epidemiological features and regularities of hand, foot and mouth disease （HFMD） in Guiizhou from 2008 to 2011, and to provide evidences for prevention and control of the disease. Methods Descriptive epidemiological analysis was conducted on the incidence data of HFMD in Guizhou during the period of 2008 -2011. Results Totally 73,918 cases of HFMD were reported in Guizhou from 2008 to 2011, and i, 127 cases were severe, in which 69 cases died. The incidence of all cases from 2008 to 2010 showed a single peak, but it was bimodal in 2011 and the second peak was between the 47th and 49th weeks of 2011. Most of the cases were infants and young children. The ratio of male to female was 1.7; 1. 89 % of the cases occurred in children aged ~5 years. Most cases were distributed in county - level cities, including Guiyang, Zunyi, Anshun, and Liupanshui. 2,218 cases were diagnosed by laboratory （accounting for 3% of total cases）, and EVT1 was the major pathogen （49% positive）. Conclusions The epidemic of HFMD in Guizhou showed an upward trend year by year. Most of the HFMD cases occurred in children aged ≤5 years. The number of severe and death cases was significantly higher than the previous years, and EVT1 was the main pathogen caused the severe and death.

关 键 词：手足口病 流行病学特征 肠道病毒71 预防 

分 类 号：R181.3[医药卫生—流行病学]