糖肾煎联合羟苯磺酸钙治疗早期糖尿病肾病的临床观察  

Clinical Efficacy of Tangshenjian with Calcium Dobesilate in the Treatment of Early Diabetic Nephropathy

作　　者：苏灏[1] 

机构地区：[1]湖北省武汉市中医医院内分泌科,湖北武汉430014

出　　处：《中国民族民间医药》2013年第3期23-23,25,共2页Chinese Journal of Ethnomedicine and Ethnopharmacy

摘　　要：目的:观察糖肾煎联合羟苯磺酸钙治疗早期糖尿病肾病的临床疗效。方法:将早期糖尿病肾病患者64例随机分为治疗组及对照组,每组32例,均采用基础糖尿病的治疗,对照组再给予羟苯磺酸钙治疗,治疗组在对照组基础上加上糖肾煎治疗。连续治疗12周以后,比较治疗前后24h尿白蛋白排泄量、肾功能(血肌酐和血尿素氮)及血糖的变化。结果:两组治疗前后差异具有统计学意义(P<0.05),与对照组比较,治疗组能明显降低24h尿蛋白排泄量,降低血糖、尿素氮及肌酐水平(P<0.05)。结论:糖肾煎联合羟苯磺酸钙能减少早期糖尿病肾病患者的尿白蛋白,改善肾功能,延缓糖尿病肾病的进展。Objective： To observe the effect of Tangshenjian combined with calcium dobesilate in treatment of early diabetic nephropathy. Methods： 64 patients with early diabetic nephropathy were randomly divided into the treatment group and control group, 32 patients in each group, which wrere treated with controlling blood sugar. Patients in the the control group only used calcium dobesilate treatment except controlling blood sugar, the treatment group used Tangshenjian and calcium dobesilate. Continuous treatment for 12 weeks, 24 h urinary albumin excretion, renal function （BUN and Cr） and blood glucose were compared before and after treatment in the two groups. Results： The results of the two groups before and after treatment was significantly different （ P 〈 0. 05 ）. Compared with the control group, 24 h urine protein excretion, reduce blood glucose, blood urea nitrogen and creatinine levels of the treatment group can significantly reduce （ P 〈0. 05 ）. Conclusion： Tangshenjian combined with calcium dobesilate can reduce urinary albumin in patients with early diabetic nephropathy, improve renal function, delay the progression of diabetic nephropathy.

关 键 词：糖肾煎 羟苯磺酸钙 糖尿病肾病 

分 类 号：R587.1[医药卫生—内分泌]