癌症化疗患者癌因性疲乏对生命质量的影响  

Investigation of the cancer-related fatigue and quality of life in cancer patients with chemotherapy

作　　者：郑瑾[1] 陈丹丹[1] 于秀月[1] 田昕玉[2] 

机构地区：[1]中国医科大学附属第一医院,110001 [2]中国医科大学

出　　处：《山西医药杂志（下半月）》2013年第2期141-143,共3页Shanxi Medical Journal

摘　　要：目的了解癌症化疗患者癌因性疲乏的状况及对生命质量的影响。方法调查154例乳腺癌、直肠癌与肺癌患者,应用癌因性疲乏自评量表(PFS)和癌症患者生命质量测定核心问卷(QLQ-C30),分别测量患者的癌因性疲乏与生命质量状况,并分析两者之间的相关关系。结果癌症化疗患者癌因性疲乏的发生率及程度较高,所有的患者都感受到疲乏,58.4%的患者为中度疲乏,40.9%的患者为重度疲乏。癌症化疗患者生命质量中躯体功能领域最差,其次为情感与认知功能,整体健康状况与社会功能领域相对较好。癌症化疗患者癌因性疲乏引起的行为严重度与整体生命质量呈负相关,疲乏量表中感知、情感与认知与生命质量的情感领域呈负相关。结论癌症化疗患者癌因性疲乏与其生命质量存在一定的相关关系,为临床护理工作提供指导。Objective Our purpose was to investigate the cancer-related fatigue and its influence on quality of life in cancer patients with chemotherapy. Methods A total of 154 cancer patients with breast cancer, intestinal cancer and pulmonary cancer were investigated. Two questionnaire were used （the revised piper fatigue scale and Quality of Life Questionnaire-Core30） to investigate the relationship between cancer-related fatigue and quality of life. Results The rate and extent of cancer-related fatigue in cancer patients with chemotherapy were both high. Fifty-eight point four perent of the patients were with moderate fatigue, while 40.9 % were with severe fatigue. In the life quality of the cancer patients with chemotherapy, physical functioning was the worst, emotional and cogni- tive functioning were in the second place, meanwhile the overall health and social functioning were relatively bet- ter. There was a significant negative correlation between the severity of behavior caused by cancer-related fatigue and the global quality of life. The domain of sensory, affective meaning, cognitive and mood were negatively cor- related with emotional functioning domain of quality of life. Conclusion There exists a certain relationship be- tween cancer-related fatigue and quality of life in cancer patients with chemotherapy.

关 键 词：肿瘤 疲劳 生活质量 

分 类 号：R473.73[医药卫生—护理学]