消痰通腑颗粒对危重患者炎性因子的影响  

Impact of Xiaotantongfu Granule on Inflammatory Factors in Critically Ill Patients

作　　者：叶敏[1] 孙大志[1] 修丽娟[1] 刘煊[1] 秦志丰[1] 施俊[1] 武峰[1] 陆烨[1] 魏品康[1] 

机构地区：[1]第二军医大学附属长征医院,上海200003

出　　处：《中国中医急症》2013年第2期184-185,188,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：军队"十二五"中医药科研专项课题(2010z131)

摘　　要：目的观察消痰通腑颗粒对危重患者炎性因子的治疗效果。方法纳入危重患者59例,分为治疗组28例,对照组31例。两组同时接受常规基础治疗,治疗组在此基础上加服消痰通腑颗粒,疗程为7 d。两组均在治疗前与治疗后检测白细胞计数、中性粒细胞计数、C反应蛋白(CRP)、白介素-6(IL-6)、内毒素(ET)、肿瘤坏死因子α(TNF-α)。结果治疗7 d后,两组白细胞计数、中性粒细胞计数、CRP、IL-6、ET、TNF-α均下降,且治疗组治疗后CRP、IL-6水平明显低于治疗前,治疗组治疗后的CRP水平明显低于对照组。结论消痰通腑颗粒可有效减轻危重患者的炎症反应。Objective： To evaluate the impact of Xiaotantongfu Granule on nflammatory factors in critically ill patients.Methods： During which 59 critically ill patients were enrolled and divided into Xiaotantongfu Granule group（28 patients） and control group（31 patients）.All patients were given basic treatment for 7 days.Patients in Xiaotantongfu Granule group were given oral Xiaotantongfu Granule 13.6g two times a day.White blood cell count、neutrophil count,CRP,IL-6,ET,TNF-α of the two groups on the first day and the last day were detected.Results： The levels of white blood cell count,neutrophil count,CRP,IL-6,ET、TNF-αof both groups decreased,and the level CRP,IL-6 of treatment group were significantly lower than before treatment.And the level of CRP after treatment was obviously lower than that of treatment.Conclusion： Xiaotantongfu Granule can effectively reducing the inflammatory response in critically ill patients.

关 键 词：消痰通腑颗粒 危重患者 炎性因子 

分 类 号：R278[医药卫生—中医学]