胎儿宫内发育迟缓与血浆AMD、PLF的关系研究  

RELATIONSHIP BETWEEN INTRAUTERINE GROWTH RETARDATION AND PLASMA ADRENOMEDULLIN AND PLACENTAL ISOFERRITIN LEVEL

作　　者：庞莲清 黄思毅 廖燕 

机构地区：[1]湛江市坡头区南调街道社区卫生服务中心,广东湛江524000 [2]湛江市第二人民医院

出　　处：《承德医学院学报》2013年第2期117-118,共2页Journal of Chengde Medical University

摘　　要：目的:探讨胎儿宫内发育迟缓(IUGR)与血浆肾上腺髓质素(ADM)和胎盘异铁蛋白(PLF)的关系,为临床防治IUGR提供新思路。方法:根据随访妊娠结局IUGR组30例、正常组30例,晚孕早期用ELISA法检测血浆ADM水平,化学分析法测定血浆PLF水平。结果:与正常组比较,IUGR组血浆ADM水平明显升高、PLF水平明显降低,差异具有统计学意义(P<0.01)。IUGR者血浆ADM水平与PLF显著负相关(r=-0.543,P<0.01)。结论:血浆ADM水平升高和PLF水平降低与IUGR的发生密切相关。Objective：To investigate the relationship between intrauterine growth retardation （IUGR） and plasma adrenomedullin （ADM） and placental isoferrifin （PLF） level, so to provide new ideas for prevention and conlrol of IUGR in clinic.Methods：The pregnant women were divided accamting to pregnancy outcome： IUGR group and normal group, each group had 30 women. At late early stage ofpregnancy, the ADM level in plasma was detected with ELASA, PLF level was detected with chemical analysis.Results：Compared with normal group, the ADM level in plasma of IUGR group increased obviously, PLF level decreased obviously （P〈 0.01 ）. For 1UGR pregnant women, ADM level in plasma and PLF level had negative correlations （r=-0.543, P〈 0.01）.Conclusions： Increasing of plasma ADM level and decreasing of plasma PLF level have close relations with occurrence of IUGR.

关 键 词：肾上腺髓质素 胎盘异铁蛋白 胎儿宫内发育迟缓 

分 类 号：R714.51[医药卫生—妇产科学]