经纤维支气管镜黏膜下注射硬化剂治疗支气管胸膜瘘观察  

The Clinical Observation of Endoscopic Submucosal Injection of Polidocanol for Bronchopleural Fistula after Lobectomy

作　　者：杜成刚[1] 

机构地区：[1]大邑县人民医院,四川成都611300

出　　处：《现代临床医学》2013年第1期46-47,共2页Journal of Modern Clinical Medicine

摘　　要：目的:探讨经纤维支气管镜黏膜下注射1%乙氧硬化醇治疗肺切除术后支气管胸膜瘘的疗效。方法:13例肺切除术后发生支气管胸膜瘘的患者均接受经纤维支气管镜黏膜下注射1%乙氧硬化醇以封闭瘘口的治疗。结果:13例支气管胸膜瘘患者瘘口直径2～7 mm,平均3.5 mm。13例患者中10例获得痊愈,3例治疗失败。10例治疗成功患者平均注射次数为2.1次(1～6次)。注射次数与瘘口大小有一定的相关性:瘘口<3 mm的7例患者均一次封堵成功,余3例患者注射次数分别为3次、5次和6次。在经纤维支气管镜硬化剂封堵治疗的过程中未发生严重的并发症及不良反应。结论:纤维支气管镜引导下注射1%乙氧硬化醇治疗支气管胸膜瘘不但可安全、有效地闭合瘘口,而且硬化剂可以重复注射,患者耐受性好且不影响后续治疗。Objective：To analyze the therapeutic effect of endoscopic submucosal injection of polidocanol for bronchopleural fistula after lobectomy. Methods： 13 patients with bronchopleural fistula after lobectomy received endoscopic multiple submucosal injection of polidocanol on the margins of the fistula. Results：The fistulas ranged from 2 mm to 7 mm（ mean, 3.5 mm） in diameter. 10 patients healed successfully, while the other 3 patients failed. Frequency of injection was correlated to the size of orificium fistulae. One - time plugging was successful in term of 7 patients with less than 3 mm orificium fistulae. However, plugging was performed for 3,5,6 times in other 3 patients. No therapy - related complications occurred in all patients. Conclusion： Endoscopic submucosal injection of polidocanol prove to be a valid and safe method for bronchopleural fistula after lobectomy.

关 键 词：支气管胸膜瘘 1%乙氧硬化醇 内镜下治疗 

分 类 号：R768.1[医药卫生—耳鼻咽喉科]