颈内动脉狭窄对眼部血流频谱形态的影响及颈内动脉切除术后眼部血流的变化  

A Study of Blood Spectrum Morphology about Ocular Ischemic Diseases Caused by Internal Carotid Stenosis and The Difference after Carotid Endarterectomy

作　　者：李琳[1] 魏世辉[2] 安立春[2] 陈洁[2] 朱丹[1] 

机构地区：[1]内蒙古医科大学附属医院眼科,内蒙古呼和浩特010050 [2]中国人民解放军总医院眼科,超声科,北京100853

出　　处：《内蒙古医学杂志》2012年第10期1159-1163,F0003,F0004,共7页Inner Mongolia Medical Journal

摘　　要：目的：分析颈内动脉狭窄对眼部血流频谱形态影响及颈动脉切除术后眼部血流变化。方法：选取2009年7~10月在解放军总医院神经外科和血管外科住院至少一侧颈内动脉狭窄并拟行颈内动脉内膜剥除术治疗患者20例,均行数字减影血管造影或核磁共振血管造影检查明确了颈内动脉狭窄率≥60%。入选患者均用超声检测视网膜中央动脉和眼动脉的收缩期血流速峰值,同时记录频谱形态。其中,接受手术治疗患者于术后第7 d再次行上述检查。结果：74.2%患侧眼动脉频谱出现改变,83.9%患侧视网膜中央动脉频谱形态出现改变。行手术治疗患者,与术前相比,眼动脉和视网膜中央动脉收缩期峰值流速术后均有增加（P〈0.05）。结论：当颈内动脉狭窄率≥60%时,眼部的球后血流频谱形态已经出现改变。从血流动力学角度和频谱形态分析,CEA可以改善眼部血供。Objective：To investigate the varied spectrum of ocular ischemic diseases caused by carotid stenosis,and the difference about ocular vessel blood velocity after CEA.Methods： The patients being treated with carotid endarterectomy（CEA） are defined the rate of internal carotid artery stenosis ≥60% by digital subtraction angiography（DSA） or magnetic resonance angiography（MRA） in neurosurgery surgery and vascular surgery departments of People＇s Liberation Army General Hospital.20 patients are selected and given eye examination and color doppler flowimaging（CDFI） for measurement of the peak systolic velocity（PSV） about ophthalmic,central retinal arteries.7 patients of 20 selected patients are treated with carotid endarterectomy（CEA）.CDFI are done again 7 days after CEA.The results are studied statistically.Results： 74.2% spectrum of ocular artery is different from before.83.9% spectrum of central retinal artery is either.PSV in the ophthalmic,central retinal arteries increased significantly 1 week after CEA（P0.05）.Conclusion：Internal carotid artery stenosis can obviously cause ocular varied spectrum.CEA can improve the ipsilateral retrobulbar blood flow.

关 键 词：颈内动脉狭窄 缺血性眼病 彩色多普勒血流成像 颈动脉内膜切除术 

分 类 号：R543.4[医药卫生—心血管疾病] R743[医药卫生—内科学]