癫痫患者伤残调整生命年的影响因素  

A study of disability adjusted life year about patients with epilepsy

作　　者：常亮[1] 冯石献[1] 常靖[2] 

机构地区：[1]河南省疾病预防控制中心健康教育与慢性非传染性疾病防治研究所,河南省郑州450000 [2]河南省肿瘤医院医务科

出　　处：《中华神经科杂志》2013年第2期87-90,共4页Chinese Journal of Neurology

基　　金：河南省医学重点学科、临床特色专科学术技术带头人培养计划资助项目（201018~6）;卫生部中央补助地方农村地区癫痫防治管理项目（财社[2006]126号）

摘　　要：目的评价癫痫患者的伤残调整生命年（DALY）及其影响因素。方法在河南省9个项目示范点采用多阶段分层随机抽样对874例癫痫患者进行调查，编制河南省居民期望寿命用于DALY测算，采用R2．10．0对DALY及其影响因素进行单因素和多因素Logistic回归分析。结果本研究地区癫痫患者的人均DALY损失值为16．64人年，每千人口DALY损失值为3．41人年。综合干预和无干预对照组的患者人均DALY损失分别为8．56、24．19人年，差异有统计学意义（Z=23．146，P〈0．01）。非条件多因素Logistic回归方程有统计学意义（X^2=365．83，P〈0．01），年龄、病程、发作频率和焦虑状况是疾病负担主要的影响因素。结论应针对重点人群、重点的可干预影响因素加强干预，应加强以“规范治疗＋随访管理与健康教育＋心理干预治疗”为主要手段的综合干预。Objective To evaluate of the disability adjusted life years （DALY） and its influencing factors in patients with epilepsy. Methods Eight hundred and seventy-four cases with epilepsy were investigated in 9 pilot sites in Henan province. Make up the life expectancy of residents in Henan province for the DALY estimates. Using the R 2. 10. 0 software, the quality-adjusted life years and its influencing factors were analyzed by univariate and multivariate analyzes. Results There was 16. 64 per capita loss of all cases of epilepsy DALY, and DALY loss value was 3.41 per 1000 populations. Comprehensive intervention and no sense of control group patients were per capita DALY loss of 8. 56 person-years and 24. 19 person-years respectively. There was significant difference between the two groups DALY loss （Z = 23. 146, P 〈 0.01 ）. Moreover, non-conditional Logistic regression equation was also statistically significant （X^2=365.83, P 〈0.01）. Age, duration, seizure frequency, compliance, and anxiety situation were the main factors of the disease burden. Conclusions In the future, enhanced interventions should be focused on the priority groups and the modifiable factors. Additionally, the ＇standard treatment ＋ follow-up management and health education ＋ psychological intervention＇ should be strengthened as a primary means of comprehensive intervention.

关 键 词：癫痫 质量校正寿命 问卷调查 危险因素 

分 类 号：R195.4[医药卫生—卫生统计学]