现在自然界和人群中已不存在非典病毒  

SARS CoV no longer exists in nature and population

作　　者：徐德忠[1] 孙慧敏[1] 谭雅慧[1] 

机构地区：[1]第四军医大学军事预防医学院军队流行病学教研室,陕西西安710032

出　　处：《医学争鸣》2013年第1期22-26,共5页Negative

摘　　要：非典(SARS)流行至今已近10年,虽被进行了全面广泛深入的研究,但其起源和贮存宿主仍不明确。我们发现SARS的流行自然史和迄今世界上的传染病均不相符,其原因是非典病毒(SARS CoV)经"非寻常进化"方式,很可能是"非自然"方式进入人群。对几乎所有的SARS CoV基因变异、进化、跨种传播等既往研究,我们进行重新审视并综合分析,发现以往研究多从微观和一个侧面思考问题,而本文则从全新之视角,结合流行病学和生物进化理论,首次阐明:SARS CoV经历了逆向进化;自然界根本不存在SARS CoV的直接祖先和贮存宿主,故其流行后即从人群和动物界消失。因此建议卫生部正式向WHO等有关国际机构申请组织专家委员会,实证自然界和人群中已无SARS CoV,并予宣布。The origin and the reservoir of SARS CoV are not yet found though with very extensive studies since SARS epidemic ten years ago. We found that the nature history of SARS epidemic is different from the rest and is against the general cpidemiological pattern of the infectious diseases in the world so far, it＇s because that SARS CoV entered into human population through an “unusual” evolution, probably “non-natural” way. We comprehensively re-examined and reanalyzed near all previous studies on gene mutation, evolution and interspecies transmission of SARS CoV and found that most of then1 were viewed from microcosmic and one-way thought. From an innovative macroscopic view and with the combination of cpidemiological method and evolutionary theory, we have first illuminated in present article that SARS CoV experiences the reverse evolution and there is no direct ancestor and reservoir of the SARS CoV in nature, therefore it disappeared in the world except the laboratories after the epidemic. So we suggest the Ministry of Health to formally apply to WHO for organizing an expert committee to confirm and announce that SARS CoV no longer exists in nature and human population.

关 键 词：SARS冠状病毒 逆向进化 流行病学 传染病消灭 

分 类 号：R18[医药卫生—流行病学]