Finite element analysis of neodymium： yttrium-aluminum-garnet incisions for the prevention of anterior capsule contraction syndrome  

作　　者：WANG Yan-ling WANG Zhen-ze ZHAO Lu XIONG Shi-hong LI Qian WANG Ning-li SUN An-qiang 

机构地区：[1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing 100730, China [2]Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China [3]Key Laboratory for Biomechanics and Mechanobiology of the Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China

出　　处：《Chinese Medical Journal》2013年第4期692-696,共5页中华医学杂志（英文版）

基　　金：This study was supported by grants from National Natural Science Foundation of China （No. 81173412）, Beijing Science and Technology Project （Z111107067311056） and Beijing Natural Science Foundation （No. 7122046）.

摘　　要：Background Anterior capsular contraction syndrome is a potential complication of continuous curvilinear capsulorhexis （CCC）. Three neodymium： yttrium-aluminum-garnet （Nd：YAG） laser relaxing incisions decrease anterior capsular contraction but the mechanism is unknown. The present study analyzed the biomechanical mechanism of three Nd：YAG laser relaxing incisions made to reduce anterior capsular contraction. Methods A three-dimensional control model and a three-dimensional Nd：YAG model of the anterior capsule with an opening diameter of 6 mm were created. Three incisions of 1 mm in length were made centrifugally at intervals of 120~ around the opening circle. The stress alterations of the anterior capsule after CCC with and without Nd：YAG relaxation were numerically simulated and compared. Results In the control model, the stress was axially uniform in the inner area and relatively high near the inner rim of the opening. Meanwhile, in the Nd：YAG model, the stress level was very low in the inner opening areas, especially near the three incisions. The relaxing incisions in the Nd：YAG model significantly released the relatively high stress on the anterior capsule. Additionally, there was a high stress gradient near the relaxing incisions. Conclusion Biomechanical effects of stress release may be the preventive mechanism of Nd：YAG incision against anterior capsular contraction syndrome.Background Anterior capsular contraction syndrome is a potential complication of continuous curvilinear capsulorhexis （CCC）. Three neodymium： yttrium-aluminum-garnet （Nd：YAG） laser relaxing incisions decrease anterior capsular contraction but the mechanism is unknown. The present study analyzed the biomechanical mechanism of three Nd：YAG laser relaxing incisions made to reduce anterior capsular contraction. Methods A three-dimensional control model and a three-dimensional Nd：YAG model of the anterior capsule with an opening diameter of 6 mm were created. Three incisions of 1 mm in length were made centrifugally at intervals of 120~ around the opening circle. The stress alterations of the anterior capsule after CCC with and without Nd：YAG relaxation were numerically simulated and compared. Results In the control model, the stress was axially uniform in the inner area and relatively high near the inner rim of the opening. Meanwhile, in the Nd：YAG model, the stress level was very low in the inner opening areas, especially near the three incisions. The relaxing incisions in the Nd：YAG model significantly released the relatively high stress on the anterior capsule. Additionally, there was a high stress gradient near the relaxing incisions. Conclusion Biomechanical effects of stress release may be the preventive mechanism of Nd：YAG incision against anterior capsular contraction syndrome.

关 键 词：anterior capsular contraction syndrome continuous curvilinear capsulorhexis three neodymium YTTRIUM-ALUMINUM-GARNET biomechanics stress 

分 类 号：TN248.13[电子电信—物理电子学] TQ336.1[化学工程—橡胶工业]