专项整治前后我院抗菌药物应用情况调查  

Survey of Antimicrobial Use in Our Hospital before and after Special Rectification

作　　者：张钰宣[1] 梅丹[1] 闫世方[1] 

机构地区：[1]中国医学科学院/北京协和医学院/北京协和医院,北京100730

出　　处：《中国药房》2013年第10期870-873,共4页China Pharmacy

摘　　要：目的:了解我院专项整治前、后抗菌药物应用各项指标的变化。方法:调取我院2010年7-11月(整治前)和2011年7-11月(整治后)抗菌药物应用基础数据,并分别计算住院患者抗菌药物应用比例、使用强度(AUD)、特殊使用类抗菌药物用量占抗菌药物总用量比例、住院患者人均应用抗菌药物费用、抗菌药物费用占药品总费用比例和Ⅰ类切口手术预防用抗菌药物比例等6项指标。结果:与整治前比较,整治后我院住院患者抗菌药物应用比例、AUD、特殊使用类抗菌药物用量占抗菌药物总用量比例、住院患者人均应用抗菌药物费用、抗菌药物费用占药品总费用比例和Ⅰ类切口手术预防用抗菌药物比例等指标的变化幅度分别为-3.10%、-18.56%、1.22%、-19.17%、-17.42%和-6.46%,其中手术科室的变化较为显著。整治后,全院50%的科室抗菌药物应用率<60%,52%的科室抗菌药物AUD<40DDDs/100人/天。结论:整治后,我院大多数科室的抗菌药物应用较整治前均有明显改善,但Ⅰ类切口手术预防用抗菌药物不十分理想,还需进一步加强宣传培训和管理。OBJECTIVE： To investigate the changes of antimicrobial use index in our hospital before and after special rectification. METHODS： The basic data of antimicrobial use were collected in our hospital during Jul.-Nov. in 2010 （before rectification） and Jul.-Nov. in 2011 （after rectification）. The proportion, AUD, the proportion of antibiotics for special use in total amount, antibiotics cost of inpatients per capita, the proportion of antibiotics cost in total drug cost and the proportion of prophylactic application of antibiotics for type Ⅰ incision were all calculated. RESULTS： Compared with before rectification, the changes of above indexes in our hospital were -3.10%,-18.56%, 1.22%,-19.17%,-17.42% and -6.46% after rectification, especially in operation department. After rectification, the percentage of antimicrobial use was less than 60% in 50% of departments of our hospital, and AUD of 52% of departments was less than 40 DDDs/100 persons/day. CONCLUSIONS： The utilization of antimiorobial have been improved significantly after rectification, but the prophyliactic application of antimicrobial are not satisfacotry for type Ⅰ iacision. The spreading, training and mangement of it should be further improved.

关 键 词：抗菌药物 专项整治 使用强度 特殊使用类 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]