综合干预措施对我院注射用抗菌药物应用的效果评价  

Effects Evaluation of Comprehensive Interventions on the Use of Antibiotics for Injection in Our Hospital

作　　者：马国辉[1] 邢颖[1] 甄健存[1] 

机构地区：[1]北京积水潭医院药剂科,北京100035

出　　处：《中国药房》2013年第10期876-878,共3页China Pharmacy

摘　　要：目的:评价实施综合干预措施对我院注射用抗菌药物应用的影响。方法:采用限定日剂量(DDD)方法,对我院实施综合干预措施前(2011年2-7月)、后(2011年8月至2012年1月)注射用抗菌药物的销售金额、用药频度(DDDs)进行回顾性分析。结果:经过实施综合干预措施,我院注射用抗菌药物销售金额从干预前的23120103.14元下降至干预后的21106680.42元,降幅达8.71%;其占药品总销售金额的比例由干预前的22.86%下降至干预后的18.42%,降幅达4.44%。青霉素类、喹诺酮类、头霉素类药的销售金额下降最为明显。头孢美唑的DDDs由干预前的7090.00下降到干预后的1818.25,下降74.36%;莫西沙星、左氧氟沙星的DDDs均有大幅下降。结论:通过实施综合干预措施,我院注射用抗菌药物应用更加趋于合理。OBJECTIVE： To evaluate the effects of comprehensive intervention on use of antibiotics for injection in our hospital. METHODS： Using DDD analysis method, the use of antibiotics for injection in our hospital before （Feb.-Jul. in 2011 ） and after intervention （Aug.2011-Jan. 2012） was analyzed retrospectively in terms of consumption sum and DDDs retrospectively. RESULTS： After the implementation of comprehensive interventions, the consumption sum of antibiotics for injection in our hospital dropped from 23 120 103.14 yuan before intervention to 21 106 680.42 yuan after intervention, dropping by 8.71% ; their proportion of the total consumption sum decreased from 22.86% before intervention to 18.42% after the intervention, dropping by 4.44% ; that of penicillins, quinolones and cephamycins decreased significantly. DDDs of cefmetazole decreased from 7 090.00 before intervention to 1818.25 after intervention, decreasing by 74.36%. DDDs of moxifloxacin and levofloxacin had dropped sharply. CONCLUSIONS： Through comprehensive interventions, antibiotics for injection is further more reasonable in our hospital.

关 键 词：抗菌药物 干预 用药频度 合理用药 

分 类 号：R969.3[医药卫生—药理学] R287[医药卫生—药学]