我院治疗药物监测全程质量控制体系初建和持续改进体会  

Experience of Establishment and Continuous Improvement of Therapeutic Drug Monitoring Quality Control System in Our Hospital

作　　者：程丽静[1] 马俊[1] 李倩[1] 赵冠人[1] 冯端浩[1] 

机构地区：[1]解放军第309医院药剂科,北京100091

出　　处：《中国药房》2013年第10期903-905,共3页China Pharmacy

摘　　要：目的:建立并优化治疗药物监测(TDM)的质量控制体系,提高血药浓度监测质量。方法:建立并完善TDM制度和标准操作规程,规范各项试验记录,分析质控结果。结果:建立并完善各种制度和仪器的标准操作规程共计34个、记录表格7个;通过质控图回顾分析质控结果,查找失控原因;定期对人员进行培训和考核。从各个环节提高了血药浓度监测值的准确性。结论:通过不同岗位的责任者共同建立TDM全程质量控制体系,为患者合理、安全、经济用药起到了越来越重要的作用。OBJECTIVE： To establish and optimize therapeutic drug monitoring （short for ＂TDM＂） quality control system, and to improve the quality of blood concentration monitoring. METHODS ： By means of establishment or improvement of TDM regulation and operation rules, all the experiments＇ records were standardized and results of quality control were analyzed. RESULTS. 34 systems and standard operation rules of equipments and 7 records were established and improved. Results of quality control were analyzed using quality control diagram to find out-of-control reasons. Regular personnel training and assessment guaranteed the accuracy of blood concentration monitoring in all aspects. CONCLUSIONS： All responsible personnel in different positions work together to establish TDM monitoring quality control system, which will play an important role in reasonable, safe and economical drug use.

关 键 词：治疗药物监测 质量控制 持续改进 

分 类 号：R95[医药卫生—药学] R97