南天竹种子中木脂素类成分研究  

Study on the Lignan Constituents in Seeds of Nandina Domestica Thunb.

作　　者：舒积成[1] 刘建群[1] 彭财英[1] 王亚莉[1] 

机构地区：[1]江西中医学院,南昌330004

出　　处：《中国现代应用药学》2013年第2期115-118,共4页Chinese Journal of Modern Applied Pharmacy

基　　金：国家自然科学基金资助项目(81102788);江西省自然科学基金项目(20114BAB215041)

摘　　要：目的研究南天竹种子的化学成分。方法采用正相硅胶、凝胶、微孔树脂、半制备高效液相柱色谱等手段分离,波谱法进行结构鉴定。结果从南天竹种子中分离得到7个木脂类化合物：丁香脂素（1）、松脂素（2）、杜仲树脂酚（3）、1-羟基松脂素（4）、gentioluteol（5）、berchemol（6）、berchemol-4＇-O-β-D-吡喃葡萄糖苷（7）。结论化合物1~7均为首次从该植物中分离得到。OBJECTIVE To study the chemical constituents of the seeds ofNandina domestica Thunb. METHODS The compounds were isolated by a variety of column chromatography and the structures of these compounds were elucidated by means of spectral analysis. RESULTS Seven lignans were isolated and their structures were identified as syringaresinol （1）, pinoresinol （2）, medioresinol （3）, 1-hydroxypinoresinol （4）, gentioluteol （5）, berchemol （6）, berchemol-4＇-O-β-D-glucoside （7）, respectively. CONCLUSION Compounds 1-7 are isolated from this plant for the first time.

关 键 词：南天竹子 化学成分 木脂素 

分 类 号：R284.1[医药卫生—中药学]