人工生物膜对家兔动脉粥样硬化的抑制作用  

THE INHIBITORY EFFECT OF LIPOSOME ON EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS

作　　者：赵蕊[1] 陈明哲[1] 郭静萱[1] 赵一鸣[1] 徐宁生[2] 刘晓勤[2] 赵春玉[2] 孟庆玲[2] 胡大鹏 

机构地区：[1]北京医科大学第三医院心血管研究室 [2]北京医科大学第一医院心血管研究室 [3]黑龙江牡丹江温春制药厂

出　　处：《北京医科大学学报》1991年第1期15-18,共4页Journal of Peking University(Health Sciences)

摘　　要：21只日本大耳白兔喂以高脂饲料,灌流脂质体,观察对动脉粥样硬化形成的作用,及其有关检测指标。结果表明,脂质体组主动脉内膜粥样硬化斑块面积、血脂各项指标及血液流变学等均显著改善。说明脂质体对动脉粥样硬化形成有显著抑制作用。We investigated if the Liposome may effect on the formation of atherosclerosis and on theparameters tested. 21 rabbits were fed high-cholesterol diet. The results showed that the size of athe-rosclerotic plaques and TC, HDL-CH, LDL-CH, HDL-PL, TG and blood viscosity were also signifi-cantly decreased. All the above results suggest that the Liposome might inhibit the development ofatherosclerosis in rabbits.

关 键 词：生物膜 动脉粥样硬化 脂质体 

分 类 号：R541.4[医药卫生—心血管疾病]