丝素共混膜在化妆品保湿效果评价中的应用初探  

The Preliminary Study on Application of Silk Fibroin in Moisturizing Efficacy Evaluation of Cosmetics

作　　者：李晓芹[1] 郑利[1] 倪梦嘉[1] 

机构地区：[1]苏州出入境检验检疫局,江苏苏州215104

出　　处：《香料香精化妆品》2013年第1期42-44,共3页Flavour Fragrance Cosmetics

基　　金：江苏省出入镜检验检疫局资助项目(2011kj12)

摘　　要：利用皮肤水分含量测试仪和水分散失测定仪,对添加不同质量分数甘油的保湿化妆品作用前后丝素共混膜的水分含量值(MMV)和经表皮水分散失值(TEWL)进行测定,以人体试验为参比,创造性地探索丝素共混膜在化妆品保湿效果评价中的应用价值,并对保湿类化妆品中保湿剂的最佳添加量做出指导。结果发现,丝素共混膜模拟体系的试验结果和人体试验具有相似的趋势,以其作为化妆品保湿效果评价的人体替代试验具有一定的可能性。MMV and TEWL on site fibroin were applied for assessing the moisturizing efficacy of cosmetics with different glycerol content cosmetics, which were determined by skin moisture content tester and water loss tester, respectively. Instead of human skin, silk fibroin was utilized in moisturizing efficacy evaluation of cosmetics. The purpose of this experiment was to explore the value of of silk fibroin in moisturizing efficacy evaluation of cosmetics and give a guidance on the appropriate per centage of moisturizing ingredients. The results showed that the silk fibroin model system and human body studies have similar trends, which provides the possibility of surrogate experimental evaluation for cosmetic moisturizing effect.

关 键 词：丝素共混膜 化妆品 保湿 MMV TEWL 

分 类 号：R318.08[医药卫生—生物医学工程]