内皮素-1在高血压患者病情预测中的意义  

作　　者：何文彤[1] 董化江[1] 单娜娜[1] 杨德慧 李伯森 单云官[1] 

机构地区：[1]武警后勤学院,天津300162 [2]民政部101所,北京100070

出　　处：《中国药业》2012年第A01期64-64,共1页China Pharmaceuticals

基　　金：国家十一五科技支撑计划课题,项目编号：2007BAK38805.

摘　　要：目的探讨高血压患者血清内皮素-1（ET-1）水平在高血压患者病情预测中的意义。方法100例高血压患者分为140～150、～160、～170、～180mmHg组各25人，测血清ET-1。结果高血压患者血清ET-1升高，且与血压水平呈正相关。结论血清ET-1浓度有助于预测高血压患者的病情。Objective To illustrate the change of ET-1 in hypertensive patients.Methods The study was carried out on 100 hypertension patients.The patients were divided in -150,-160,-170,-180 mmHg.25 healthy subjects were recruited as controls. ET-1 in plasma were measured with RIA method.Results Different ET-! concentrations with different blood pressure （P 〈 0.05）. ET-1 was progressive increased with the progress blood pressure.Conclusion ET-1 in plasma was increased in patients,ET-1 could predict the developing of the hypertension.

关 键 词：高血压 内皮素-1 病情预测 

分 类 号：R541.3[医药卫生—心血管疾病]