重症肺炎儿童食管动力学的研究  

Mechanisms of gastroesophageal reflux in children with severe pneumonia

作　　者：罗燕军[1] 周晓勤[1] 

机构地区：[1]湖北省妇幼保健院儿内科,湖北武汉430070

出　　处：《临床荟萃》2013年第3期273-274,277,共3页Clinical Focus

摘　　要：目的本研究的目的在于确定重症肺炎儿童食管动力学的变化。方法重症肺炎儿童25例(肺炎组)和正常儿童10例(对照组)进行连续食管pH监测和食管动力学监测,监测时间包括鼻饲前1小时和餐后3小时。结果重症肺炎儿童胃食管反流(GER)发生率为84.0%(21/25);正常儿童GER发生率为20.0%,两组比较差异有统计学意义(χ2=12.990,P<0.01)。重症肺炎组无效食管运动(IEM)发生率为72.0%(18/25),明显高于对照组(20.0%)(χ2=15.770,P<0.01)。结论重症肺炎儿童胃食管反流发病率高,表现为酸反流次数增加,酸清除能力降低,与IEM增加有关,改善食管动力可能抑制重症肺炎儿童的反流。Objective To determine the mechanisms underlying gastroesophageal reflux（GER） in children with severe pneumonia in the pediatric intensive care unit（PICU）. Methods In 25 children with severe pneumonia in PICU and 10 normal children（control）, esophageal motility and pH were recorded for 1 hour before and 3 hours after nasogastric feeding. Results Twenty-one of 25 children （84.0 %） in severe pneumonia were diagnosed as GER,while 2 of controls （20.0%） were GER（χ^2= 12. 990, P 〈0.01）. The prevalence of ineffective esophageal motility （IEM） （72.0M） was significantly higher than that in control group （20.0%） （χ^2=15. 770, P 〈0.01）. Conclusion GER is popular in children with severe pneumonia. GER in children with severe pneumonia is predominantly due to IEM.

关 键 词：肺炎 胃食管反流 儿童 

分 类 号：R563.1[医药卫生—呼吸系统]