291例药品不良反应报告分析  

Analysis of 291 ADR Case Reports in Our Hospital During 2008-2010

作　　者：余雄杰[1] 刘生友[1] 

机构地区：[1]湖北省武汉亚洲心脏病医院,武汉430022

出　　处：《中国药事》2013年第1期115-117,共3页Chinese Pharmaceutical Affairs

摘　　要：目的了解我院药品不良反应(ADR)的发生特点,促进临床合理用药。方法对我院2008～2010年间收集到的291例ADR报告进行回顾性分析。结果ADR多发生在40～59岁年龄组;循环系统用药、抗感染药及造影剂发生ADR所占的比例较大;临床表现以皮肤及消化系统损伤最为常见;静脉给药方式更易发生ADR;多数患者发生ADR经停药及对症处理后好转或治愈,对原患疾病影响不明显。结论应加强医护人员的素质培养,开展全方位的ADR监测工作,以减少ADR发生。Objective To study the occurrence characteristics of adverse drug reactions in our hospital, so as to improve the rational drug use in clinic. Methods Totally 291 ADR cases collected from our hospital between 2008 and 2010 were retrospectively analyzed. Results ADR occurred frequently in the 40-59 years age group; ADR induced by circulatory system drugs, anti-infectives and the contrast agent shared a larger proportion; the most common clinical manifestation was the skin and digestive system damage; intravenous drug delivery was the main route of administration; Most patients were improved or cured after discontinued drugs use and symptomatic treatment; moreover, the effect was not obvious for patients suffering from the original diseases. Conclusion In order to reduce the occurrence of ADR, we should strengthen the professionals and the quality of training, and carry out a full range of ADR monitoring.

关 键 词：药品不良反应 监测 报告 分析 

分 类 号：R994.11[医药卫生—毒理学]