贵州小型猪胃肠黏膜淋巴组织分布规律研究  

The research of lymphoid tissue distribution in gastrointestinal mucosa of Guizhou miniature pig

作　　者：刘霞[1] 郑邦英[1] 郭俊峰[1] 钱宁[2] 吴曙光[2] 王明镇[2] 王平[3] 田维毅[3] 

机构地区：[1]贵阳中医学院组织学与胚胎学教研室,贵阳550002 [2]贵阳中医学院实验动物研究中心,贵阳550002 [3]贵阳中医学院微生物教研室,贵阳550002

出　　处：《黑龙江畜牧兽医》2013年第3期1-2,7,165,共4页Heilongjiang Animal Science And veterinary Medicine

基　　金：贵州省科技基础条件平台项目(黔科平台[2009]4008)

摘　　要：为了观察贵州小型猪(Sus Scrofa domestica var.mino Guizhounensis Yu.)胃肠黏膜淋巴组织的分布特点,研究随机抽取封闭群健康成年贵州小型猪,采集胃肠道组织,常规H.E.染色,观察和分析其淋巴组织的分布规律。结果表明:成年贵州小型猪胃黏膜淋巴细胞主要分布于固有层;小肠黏膜的淋巴细胞较胃黏膜极显著增加(P<0.01),且从十二指肠到回肠呈上升趋势;回肠固有层及黏膜下层可见集合淋巴小结;大肠黏膜淋巴细胞由上至下呈减少趋势(P<0.01)。胃肠黏膜各段均可见上皮内淋巴细胞,其中以小肠最多,且从十二指肠到回肠呈下降趋势,大肠次之,胃黏膜最少。说明成年贵州小型猪胃肠黏膜淋巴组织分布规律与人及大鼠、小鼠等哺乳动物相似,以小肠最丰富,大肠其次,胃黏膜最少;小肠三段黏膜淋巴组织呈上升趋势,回肠最丰富,而大肠黏膜淋巴组织则呈下降趋势。To observe the distrbution characteristics of the lymphoid tissue in gastrointestinal mucosa of Guizhou miniature pig （ Sus Scrofa dom- estica var. mino guizhounensis Yu. ）, the healthy and adult Guizhou miniature pigs were randomly selected , and the tissues of the gastrointestinal tract were collected, and then hematoxylin - eosin staining was used to observe and analyze the lymphoid tissue distribution in gastrointestinal mucosa of Guizhou miniature pig. The result showed that the lymphocytes in gastrointestinal mucosa of Guizhou miniature pig were mainly located in lamina propria. The lymphocytes in small intestinal mucosa were highly significantly increased （P 〈 0.01 ） compared to that of in the gastric mucosa , showing upward trend from the duodenum to the ileum. There are many Peyer＇ s patches observed in the lamina propria of ileum and submucosa. A decreasing trend was found from top to bottom in the lymphocytes of large intestinal mucosa （P 〈0.01 ）. The intraepithelial lymphocytes were found in all of the gastrointestinal mucosa, most of them were located in the small intestine, with a decreasing trend from the duodenum to the ileum. It was followed by the large intestine, at least in gastric mucosa. The results indicated that the lymphoid tissue distribution in gastrointestinal mucosa of Guizhou miniature pig was similar to that of in humans, mice, rats and other mammals. The highest density of lymphoid tissue was found in the small intestinal mucosa, the second in large intestinal mucosa and at least in the gastric mucosa. An upward trend was found in the lymphoid tissue of three sections of mucosa in the small intestine, and the highest density of lymphoid tissue was found in the ileum, with a decreasing trend in lymphoid tissue of large intestine.

关 键 词：贵州小型猪 胃肠黏膜 淋巴组织 

分 类 号：S828.8[农业科学—畜牧学]