IgG、C_3在莱姆病皮肤慢性游走性红斑病变中的表达  

Expression of IgG and C_3 in skin lesions of erythema chromicum migrans in Lyme's disease

作　　者：安京媛[1] 吴霞[2] 周国萍[2] 艾承绪[3] 王美娥[1] 潘惠娟[1] 李全民[1] 霍云燕[3] 

机构地区：[1]武警总医院病理科,100039 [2]北京军区总医院 [3]解放军总医院

出　　处：《诊断病理学杂志》2000年第1期39-41,I014,共4页Chinese Journal of Diagnostic Pathology

摘　　要：目的　探讨IgG、C3 在莱姆病皮肤慢性游走性红斑病变中的分布和表达。方法　应用微波免疫组化S P法检测了 9例莱姆病和临床疑诊为莱姆病患者的皮肤慢性游走性红斑病变组织 ,观察病变组织中IgG和C3 的表达并与正常人皮肤组织对照。结果　研究发现IgG和C3 阳性表达的强度以及分布范围在病变组织角质层和颗粒层较显著。 4例莱姆病患者血清学检查、病变组织硝酸银染色、IgG、C3 免疫组化染色结果均呈阳性。结论　IgG、C3Object To study the expression and distribution of IgG and C 3 in skin lesions of erythema chromicum migrans in Lyme's disease. Method Nine bioptic skin specimens of clinically diagnosed and suspected Lyme's disease were examined with the S P method of immunohistochemical staining to detect the presence of IgG and C 3. Four specimens of normal skin were used as controls. Result IgG and C 3 were positively stained in all the specimens examined. Conclusion Formation of erythema chromicum migrans is associated with the expression of IgG and C 3.

关 键 词：IGG C3 莱姆病 慢性游走性红斑 

分 类 号：R514.06[医药卫生—内科学] R758.620.2[医药卫生—临床医学]