新生儿轮状病毒研究进展  

Research progress on rotavirus in neonates

作　　者：李玉静[1] 杨学磊[2] 

机构地区：[1]石河子大学医学院,新疆石河子832002 [2]新疆维吾尔自治区人民医院

出　　处：《现代预防医学》2013年第5期832-833,839,共3页Modern Preventive Medicine

基　　金：国家自然科学基金项目(No.30760232);益普生腹泻研究基金项目(IDF-2007-12)

摘　　要：近年来新生儿RV感染有所增加,且新生儿中流行的基因型与婴幼儿有所不同。一些弱毒株在新生儿体内经过重配、重组、突变等,使毒力增强或形成新的组合型,然后感染婴幼儿,成为婴幼儿中的罕见基因型,易造成腹泻暴发流行。本文就新生儿感染RV的特点和分子流行状况加以综述。Infection of rotavirus （RV） in neonates increased in recent years, epidemiological genotypes were different between neonates and children. The virulence of some strains reinforced or became new combination genotypc in neonates through reas- sortment, recombination, mutation and so on, these strains infected children and formed novel strains, caused easily caused the outbreak of diarrhea. We reviewed the characteristics and molecular epidemiology of rotavirus among neonates.

关 键 词：新生儿 轮状病毒 基因型 

分 类 号：R373.2[医药卫生—病原生物学]