从“内皮-胶质细胞信息网络”解析“脑络”功能的研究思路探索  

Analyzing function of brain collaterals from endothelial-glial cell information network

作　　者：李卫红[1] 李澎涛[2] 朱元[3] 盖聪[1] 刘洋[1] 贾静[1] 

机构地区：[1]北京中医药大学基础医学院,北京100029 [2]北京中医药大学附属东直门医院 [3]江苏省中医院

出　　处：《北京中医药大学学报》2013年第2期92-95,共4页Journal of Beijing University of Traditional Chinese Medicine

基　　金：教育部科学技术研究重点资助项目(No.109023);国家重点基础研究发展计划(973计划)资助项目(No.2012CB518600);北京中医药大学研究基地资助项目(No.2011-JDJS-10)

摘　　要：通过对属于中医"络病"范畴的一些脑病的病理机制研究和治疗现状的分析,发现由脑微血管内皮细胞、星形胶质细胞以及相互之间传递信息的细胞因子构成的"内皮-胶质细胞信息网络"紊乱可能是脑络病变的病理基础,也是中西医对脑病"络病"认识的交叉点,以此作为研究脑络理论的切入点,将有望对中医脑病的"络病"机制作出更为合理的解释,也为"通络"治疗针对的核心病理环节提供依据。Through analyzing belonging to the category of ＂ the pathological mechanisms and current treatment of some brain diseases collateral disease＂ in Chinese medicine, the authors found that the patho- logical basis of brain collateral disease is the disorder of endothelial-glial cell information network consis- ted of cerebral microvascular endothelial ceils, astrocytes and cytokines for transmitting information mutu- ally. It is also a crosspoint of understanding on collateral disease in brain diseases by Western and Chi- nese medicine, and a pointcut of research on theory of brain collaterals. The study will give a more rea- sonable explanation on collateral disease in TCM brain diseases, and provide the proof for the kernel pa- thology aimed at by treatment of freeing collaterals.

关 键 词：内皮-胶质细胞信息网络 脑络 络病 

分 类 号：R2-03[医药卫生—中医学]