砂烫马钱子炮制工艺优选  

Optimization of Processing Technology of Strychnos nux-vomica Heated with Sand

作　　者：徐颖[1] 刘玉杰[1] 孙涛[1] 吴纯洁[1] 

机构地区：[1]成都中医药大学,成都610075

出　　处：《中国实验方剂学杂志》2013年第5期25-28,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：中医药行业科研专项(201107008)

摘　　要：目的:优选砂烫马钱子的炮制工艺参数,以有效控制马钱子质量。方法:采用正交试验法,以马钱子碱、士的宁含量为指标,评价油砂粒度、砂料比、炒制温度、炒制时间对马钱子质量的影响。结果:最佳炮制工艺为中砂(300～600μm),砂料比7∶1,炒制温度(190±5)℃,炒制时间4 min。结论:优选的炮制工艺稳定可行,适用于大规模生产。Objective：To optimize processing technology parameters of Strychnos nux-vomica heated with sand,in order to control quality of S. nux-vomica effectively. Method： With the content of brucine and strychnine as indexes,orthogonal test was used to evaluate effect of oil-sand degree,sand-material ratio,frying temperature and time on processing technology parameters of S. nux-vomica. Result： Optimum processing technology parameters were as followings：medium sand （300-600 μm）,sand-material ratio 7∶1,frying temperature （190±5） ℃,frying time 4 min. Conclusion： Optimized processing technology was suitable and feasible,it was suitable for mass production.

关 键 词：马钱子 砂烫法 正交试验 炮制工艺 

分 类 号：R283.6[医药卫生—中药学]