中西医结合治疗肾阴虚型2型糖尿病30例  

30 Cases of Combine Traditional Chinese and Western Medicine in Treatment of Type 2 Diabetes Mellitus of Kidney-Yin Deficiency

作　　者：金吉[1] 董春旻[1] 苑军伟[1] 崔冠群[2] 董宇翔[1] 

机构地区：[1]吉林大学第一医院,长春130021 [2]吉林大学中日联谊医院,长春130033

出　　处：《中国实验方剂学杂志》2013年第5期317-320,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:探讨中西医结合治疗肾阴虚型2型糖尿病的临床疗效。方法:选择符合标准病例60例,随机分为治疗组与对照组,每组患者30例。两组均给予口服盐酸二甲双胍片的西药基础治疗,治疗组加服滋阴补肾方治疗。连续用药60日后观察两组患者综合证候疗效,空腹血糖(FPG)、餐后2 h血糖(P2hPG)、糖化血红蛋白(HbA1c)及血脂中总胆固醇(TC),高血症(TG),低密度脂蛋白胆固醇(LDL-C)与高密度脂蛋白胆固醇(HDL-C)变化,评价治疗疗效。结果:治疗后治疗组与对照组比较,综合证候疗效差异具有统计学意义(P<0.05);FPG,P2hPG,HbA1c疗效差异均具有统计学意义(P<0.05);血脂中TC,TG疗效差异有统计学意义(P<0.05),LDL-C,HDL-C疗效差异无统计学意义。结论:中西医结合治疗肾阴虚型2型糖尿病能够有效改善患者临床综合证候,降低血糖,调节血脂,值得临床推广。Objective：To approach the effect of the treatment of type 2 diabetic patients of kidney Yin deficiency with combine traditional Chinese and Western medicine. Method： Sixty selected standard cases were randomly divided into treatment group and control group, each group with 30 cases. The two groups were both given oral metformin hydrochloride tablet for western medicine therapy, but the prescription for nourishing the Kidney-Yin was added to the therapy for the treatment group. The changes of syndrome efficacy,fasting plasma glucose（FPG）, postprandial 2 hours plasma glucose（P2hPG）, hemoglobin A1c（HbA1c）, and, hyperlipidemiu（TG）, total cholesterol（TC）, low density lipoprotein-cholesterol（LDL-C） and high density lipoprotein-cholesterol（HDL-C） in serum lipid were observed after 60 days medication. And then treatment efficacy was evaluated. Result： The treatment group comparing with the control group after treatment： the difference of syndrome efficacy was statistically significant（P＜0.05）; the effects of FPG, P2hPG and HbA1c were statistically significant difference（P＜0.05）; the difference of the effects of TG and TC in blood lipid between the two groups was statistically significant（P＜0.05）, but the effects of LDL-C and HDL-C in blood lipid of comparative differences had not statistically significant. Conclusion： Treatment of type 2 diabetes mellitus of Kidney-Yin deficiency with traditional Chinese and Western medicine can effectively improve patient clinical syndrome, reduce blood sugar, and regulate blood lipids. So it was worthy of clinical application.

关 键 词：中西医结合 治疗 肾阴虚 2型糖尿病 

分 类 号：R287[医药卫生—中药学]