关于中药炮制机制研究现状与发展趋势的思考  

Thinking About Present Situation and Development Trend of the Mechanism During Traditional Chinese Medicine Processing

作　　者：高飞[1] 傅超美[1] 胡慧玲[1] 王战国[2] 毛茜[1] 傅舒[1] 

机构地区：[1]成都中医药大学药学院/中药材标准化教育部重点实验室中药资源系统研究与开发利用省部共建国家重点实验室培育基地,成都611137 [2]四川大学生命科学学院,成都610064

出　　处：《中国实验方剂学杂志》2013年第5期352-355,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金青年基金项目(81001638)

摘　　要：通过对近几年有关中药炮制机制研究文献进行分析,结合自身科研经验,总结中药炮制机制研究的主流方法与思路。探讨中药炮制前后化学成分量与质的变化或比较中药炮制前后药效或毒性作用的变化(强与弱、改变)是中药炮制机制研究的主流思路,除此之外,还应当重视中药炮制前后全化学成分差异性、体内药动学差异性、炮制前后配伍差异性等方面的分析,多学科、多层次、全方位地构建中药炮制机制创新研究模式,才有利于挖掘中药炮制的现代科学内涵,丰富中药炮制理论,促进中药炮制学科的快速发展。Summarize the main methods and thoughts about the mechanism research of traditional Chinese medicine（TCM） processing by analyzing articles about mechanism research of TCM processing in recent years and combining with our own research experience. At present, discussing the content change and the qualitative change of the chemical component, and the change of efficacy or change of toxic effect （strong or weak or change）of the herbs before and after processing are the main thoughts of the mechanism research of TCM processing. Besides, we should pay attention to the analysis about the otherness of all chemical components, otherness of pharmacokinetic and otherness of compatibility of medicines of the TCM before and after processing. Building much discipline, multi-level and comprehensive innovation study mode of TCM processing mechanism are making for digging the modern scientific connotation of TCM processing, enriching the theory of TCM processing and promoting the rapid development of TCM processing subject.

关 键 词：中药炮制 机制 研究现状 发展趋势 

分 类 号：R284.1[医药卫生—中药学] R285[医药卫生—中医学]