弓形虫感染与男性不育研究新进展  

New advances in the study of Toxoplasma gondii infection and male sterility

作　　者：汪涛[1] 汤自豪[1] 

机构地区：[1]九江学院基础医学院病原生物学教研室,江西九江332000

出　　处：《中国病原生物学杂志》2013年第1期87-88,73,共3页Journal of Pathogen Biology

基　　金：江西省教育厅科技项目(No.GJJ12624);高层次人才引进科研启动项目(No.8870909)

摘　　要：弓形虫是一种专性细胞内寄生的原虫,能感染包括人在内的所有温血动物。众所周知弓形虫感染孕妇可导致早产、流产、死胎、畸胎等严重后果,而弓形虫感染导致的男性不育却长期未受到足够重视。本文就近年来有关弓形虫感染致精子、生殖细胞的损伤以及睾酮和一氧化氮(NO)分泌的异常而致男性不育的相关研究进展进行综述。Toxoplasma gondii is an intracellular protozoan parasite that infects all warm-blooded animals, including humans. Serious sequelae of toxoplasmosis in pregnant women include premature delivery, miscarriages, fetal death, and fetal abnormalities. However, little emphasis has been placed on male sterility as a result of toxoplasmosis. This article reviews recent research on the effect of toxoplasmosis on sperm, germ cells, testosterone and nitric oxide levels.

关 键 词：弓形虫 精子 生殖细胞 睾酮 一氧化氮(NO) 男性不育 综述 

分 类 号：R382.5[医药卫生—医学寄生虫学]