C肽、皮质醇和甲状腺激素在判断脑外伤预后中的作用  

The role of serum C peptide、cortisol and thyroid hormone in predicting the prognosis of acute brain injury patients

作　　者：张新庆[1] 程爱国[1] 庞琳[2] 韩向午[2] 

机构地区：[1]华北煤炭医学院附属医院神经外科,唐山063000 [2]华北煤炭医学院预防医学系

出　　处：《急诊医学》2000年第5期314-316,共3页

摘　　要：目的 :评价C 肽、皮质醇和甲状腺激素在急性脑外伤伤情判断和预后预测中的作用。方法 :急性脑外伤患者 74例 ,对照 35例 ,分别测定血清中各有关激素含量。采用多因素Logistic回归分析方法分析其与伤情和预后的关系。结果 :伤后 12h内的C 肽和 3日时的rT3 与伤情关系密切 ;3日时的皮质醇 (COR)和C 肽则对预后的预测意义重大 ,并分别建立了回归方程。结论 :借助于多因素分析方法只需测定个别激素指标即可对伤情和预后作出判断 ,并且CObjective:To evaluate the role of serum c peptide,cortisol and thyroid hormone in forecasting the prognosis of acute brain injury patients.Methods:Thirty five controls and seventy four cases of acute brain injury who were being hospitalized within 12hrs after injury,had their serum levels of c peptide,cortisol and thyroid hormone examined.The relationship to the severity of injury and the prognosis were analyzed by the multiple Logistic Regression analysis.Results:The results showed that the levels of c peptide in 12hrs and rT 3 3 days after injury correlated with the severity damage,so did the COR and c peptide levels 3days after injury with the prognosis.Conclusions:Among the endocrine indices examind,very few correlated with degree of injury and the prognosis.Monitoring the c peptide seemed to be more informative

关 键 词：脑外伤 C-肽 皮质醇 甲状腺激素 预后 

分 类 号：R651.1[医药卫生—外科学]