鼠带蒂肾上腺自体移植术的研究  

Adrenal allotransplantation with vessel anastomosis in rat

作　　者：刘定益[1] 齐世杰[2] 徐大生[2] 陈惠方[2] 

机构地区：[1]上海第二医科大学附属瑞金医院泌尿外科,200025 [2]加拿大蒙特利尔大学器官移植研究中心

出　　处：《中华实验外科杂志》2000年第6期546-547,共2页Chinese Journal of Experimental Surgery

摘　　要：目的　探讨临床肾上腺带蒂移植小血管吻合方法的改进。方法　采用显微外科技术 ,进行鼠肾上腺带蒂移植。经假手术组 (6只 ) ,双侧肾上腺切除组 (6只 ) ,肾上腺移植组 (6只 )的术后存活观察、内分泌检测及病理检查进行比较。结果　双侧肾上腺切除组血、尿醛固酮值明显下降 ,平均存活 6 .8d。而肾上腺移植组术后 1、14d尿醛固酮值分别达术前的 2 2 0 .6 %和 10 6 .1%。术后能长期存活。结论　通过显微外科技术可以成功完成肾上腺带蒂自体移植术。Objective\ In order to overcome the difficult of small vessel anastomosis in clinical adrenal allotransplantation with vessel.Methods\ Author underwent adrenal allotransplantation with vessel using microsurgical technique in inbred rats.The endocrinic function,graft survival and pathology were followed in 6 sham operated rats, 6 biadrenalectomy rats, 6 adrenal allotransplantation rats. Results\ Blood and urine aldosterone levels of biadrenalectomy group were significantly decreased.Average postoperative survival time was 6.8 day.Urire aldosterone at 1 and 14 day postoperation were 220.6% and 106.1% of that preoperation respectively. Long term survival was presented in allotransplantation group.Conclusion\ Adrenal allotransplantation can be successfully performed by microsurgical technique.\;

关 键 词：带蒂肾上腺移植 显微外科 自体移植 术式改进 

分 类 号：R699[医药卫生—泌尿科学]