四君子颗粒抗脾虚动物胃肠细胞损伤的研究  

The Function of Resistance Gastro-intestinal Cellular Damage of “Si- Jun-Zi” Granula to Splenic Asthenia Animal Model

作　　者：曹小玉[1] 杨智梅[2] 彭成[1] 

机构地区：[1]成都中医药大学,四川成都610075 [2]华西医科大学电镜室

出　　处：《成都中医药大学学报》2000年第3期32-33,64,共2页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：国家新药研究基金!:96 90 1 0 5 192;四川省重点科技项目!:98 140 ;四川省学术技术带头人培养基金!:498992 0

摘　　要：选用食醋“脾虚”动物模型 ,研究四君子颗粒对胃肠上皮细胞的影响。结果表明四君子颗粒能改善脾虚症状 ,纠正胃肠病损 ,消除细胞变性、坏死脱落的病理变化 ,恢复细胞、亚细胞、细胞连接的形态 ,增加细胞表面微绒毛、细胞质颗粒和细胞器的数量。提示四君子颗粒具有胃肠细胞保护、抗脾虚动物胃肠细胞损伤的作用。The splenic asthenia animal model was made by the method of feeding vinegar to study the influence of “Si-Jun-Zi” granula to gastro-intestinal epithelial cell. The results showed that “Si-Jun-Zi” granula could improve the symptoms of splenic asthenia, correct gastro-intestinal cellular damage eliminate cell degeneration and recover the shape of cell junction, increase the quantity of cell surface microvillus, cytoplasm drops. It was suggested that “Si-Jun-Zi” granula had the function of gastro-intestinal cellular protection and resistance gastro-intestinal cellular damage to splenic asthenia animal model.

关 键 词：四君子颗粒 脾气虚证 胃肠细胞损伤 中医药治疗 

分 类 号：R256.3[医药卫生—中医内科学] R285.5[医药卫生—中医学]