贵阳城区糖尿病、糖尿病前期流行病学调查及危险因素分析  

Epidemiological characteristics analysis of diabetes mellitus and prediabetes in adult population of Guiyang city

作　　者：张巧[1] 时立新[1] 彭年春[1] 庄惠君[1] 徐淑静[1] 张淼[1] 陈爽[1] 刘璐[1] 

机构地区：[1]贵阳医学院附属医院内分泌科,550004

出　　处：《中华内分泌代谢杂志》2013年第2期144-147,共4页Chinese Journal of Endocrinology and Metabolism

摘　　要：2011年5月至2011年8月随机抽取贵阳市主城区云岩区40～78岁常驻居民10 140名。年龄标化后糖尿病患病率为21.2%（男性23.6%，女性18.8%），糖尿病前期患病率为32.5%（男性34.0%，女性31.1%）。新诊断糖尿病为60%。贵州40～78岁的成年人有295.3万糖尿病患者及421.3万糖尿病前期人群。随着年龄的增长（40～49，50～59，60～69，≥70岁），糖尿病及糖尿病前期患病率快速增长（分别为13.9%,19.3%,28.7%和35.0%对29.0%,32.1%,35.7%和35.1%，均P〈0.01）；随着体重指数增加，糖尿病及糖尿病前期患病率亦呈现快速增长（分别为14.6%,19.6%,26.5%和31.6%对23.8%,30.7%,36.3%，36.4%，均P〈0.01）。单纯糖耐量受损的患病率明显高于空腹血糖受损（男性17.7%对7.6%，女性18.7%对5.5%，均P〈0.01）。糖尿病及糖尿病前期患病率男性均显著高于女性（分别为27.8%对21.6%，35.0%对32.4%，均P〈0.01）。糖尿病患病风险与男性、增龄、糖尿病家族史、肥胖、高血压、高甘油三酯及高低密度脂蛋白胆固醇显著相关。Population-based cross-sectional studies on diabetes were performed in 10 140 randomly selected adults, aged 40-78 years, living in the Yunyan community in Guiyang of Guizhou, were investigated from May, 2011 to August, 2011. The age-standardized prevalence of total diabetes and prediabetes were 21.2%（23.6% for men and 18.8% for women） and 32.5%（34.0% for men and 31.1% for women）, respectively. 60% of them were newly-diagnosed. The prevalence of diabetes and prediabetes increased with increasing age（13.9%, 19.3%, 28.7%, and 35.0% for diabetes, 29.0%, 32.1%, 35.7%, and 35.1% for prediabetes, in subjects aged 40-49, 50-59, 60-69, and ≥70, respectively）, and with increasing body mass index（BMI; 14.6%, 19.6%, 26.5%, and 31.6% for diabetes, 23.8%, 30.7%, 36.3%, and 36.4% for prediabetes, in subjects with BMI in the range of 〈18.5, 18.5-23.9, 24.0-27.9, and ≥28.0 kg/m2, respectively）. The age-adjusted prevalence of diabetes and prediabetes in males were significantly higher than in females（P〈0.01）. The prevalence of isolated impaired glucose tolerance was higher than that of isolated impaired fasting glucose（17.7% vs 7.6% in men, and 18.7% vs 5.5% in women）. In the multivariable, multinomial, logit models, male sex, older age, a family history of diabetes, overweight, obesity, central obesity, increased heart rate, elevated systolic blood pressure, elevated serum triglyceride level, and educational level below college were all significantly associated with an increased risk of diabetes and prediabetes.

关 键 词：糖尿病 流行病学研究 危险因素 

分 类 号：R587.1[医药卫生—内分泌]