声触诊组织量化技术无创评价移植肾状态的初步研究  

Noninvasive assessment of renal allograft status by virtual touch tissue quantification technique

作　　者：何婉媛[1] 李超伦[1] 季正标[1] 王文平[1] 邱甬鄞[1] 

机构地区：[1]复旦大学附属中山NNNNN上海市影像医学研究所,上海200032

出　　处：《中华超声影像学杂志》2013年第2期130-132,共3页Chinese Journal of Ultrasonography

基　　金：上海市重点学科建设项目（NoB112）

摘　　要：目的探讨声触诊组织量化（VTQ）技术在移植肾评价中的临床价值。方法移植肾患者72例，其中正常组38例，急性排异组20例，慢性移植物肾病组14例，常规超声测量移植肾主肾动脉、段间动脉、叶间动脉收缩期峰值流速（PSV）和阻力指数（RI），采用VTQ技术测量不同状态移植肾皮质的剪切波速度（SWV）。结果移植肾各分支动脉PSV在各组间差异无统计学意义，慢性移植物’肾病组各分支动脉RI高于正常组和急性排异组（P〈0．05）；正常组、急性排异组和慢性移植物。肾病组SwV分别为（2．28±0．24）m／s、（2．67±0．27）m／s和（2．90±0．31）m／s，各组问差异均有统计学意义（P〈0．05）。结论VTQ技术可作为无创评价移植肾状态的一种新技术。Objective To evaluate the feasibility of virtual touch tissue quantification （VTQ） for the assessment of renal allograft. Methods A total of 72 kidney recipients were examined with conventional ultrasound and VTQ after transpantation. Biopsies were performed in 34 patients, 20 patients were with acute rejection （AR）,14 with chronic allograft nephropathy （CAN）,38 patients as control group. The peak systolic velocity （PSV） and resistance index（RI） were measured on main, infrarenal and arcuate arteries with conventional ultrasound and shear wave velocity （SWV） of the renal cortex was obtained by VTQ. All the data were compared among three groups. Results There were no significant differences of PSV between two groups. An increased RI was presented in the CAN group（ P d0.05）. The mean SWV was （2.67 ± 0.27） m/s, （2.90± 0.31 ） m/s and （2.28 ± 0.24） m/s for AR, CAN and normal group, respectively. There were significant differences of SWV among the three groups （ P 〈 0.05）. Conclusions VTQ technique could provide a new method for the assessment of transplanted kidney.

关 键 词：超声检查 肾移植 移植物排斥 声触诊组织量化 

分 类 号：R445.1[医药卫生—影像医学与核医学]