卡贝缩宫素预防宫缩乏力性产后出血的临床观察  

Carbetoein in the prevention of postpartum hemorrhage caused by uterine inertia

作　　者：惠薇[1] 李艳秋[1] 叶凤英[1] 

机构地区：[1]南方医科大学附属何贤纪念医院妇产科,广州511400

出　　处：《国际医药卫生导报》2013年第3期362-364,共3页International Medicine and Health Guidance News

摘　　要：目的探讨卡贝缩宫素预防宫缩乏力性产后出血的临床疗效。方法随机选取我院200例自然妊娠孕妇，分为实验组和对照组，各100例，在胎儿娩出时，实验组使用卡贝缩宫素，对照组使用缩宫素，观察两组产妇出血及Hb浓度变化情况。结果实验组术中出血量、术后24小时出血量均明显少于对照组，产后出血发生率分别为2．0％和7．0％，结果相比均具有统计学意义（P〈0．05）。同时，实验组术后24小时Hh下降幅度明显小于对照组，结果有统计学意义fP〈0．05）。结论卡贝缩宫素能有效降低产妇产后出血率，疗效显著，明显优于其他宫缩剂，值得临床推广。Objective To investigate the clinical efficacy of carbetocin in the prevention of postpartum hemorrhage caused by uterine inertia. Methods 200 women with spontaneous pregnancy were randomly divid- ed into a study group and a control group, 100 for each group. As the baby was delivered, the study group re- ceived carbetocin while the control group received oxytocin. Maternal bleeding and changes in Hb concentration were observed in both groups. Results Intraoperative bleeding volume and 24-hour postoperative bleeding volume were significantly smaller in the study group than in the control group ; the incidence rate of postpartum hemorrhage was 2.0% and 7.0%, respectively, with a statistical significance between the two groups （P〈0.05）. Meanwhile, the declined level of Hb was significantly less in the study group than in the control group, with a statistical significance （P〈0.05）. Conclusions Carbetocin can effectively reduce postpartum hemorrhage with good efficacy and is much better than any other tocolytic agents. It is worth popularizing.

关 键 词：卡贝缩宫素 宫缩乏力 产后出血 

分 类 号：R714.461[医药卫生—妇产科学]