吸入丙酸倍氯米松治疗婴幼儿哮喘的疗效观察  

Efficacy of inhalation of beclomethason in the treatment of asthma in infants and young children

作　　者：陈育智[1] 曹玲[1] 刘世英[2] 向莉[2] 陈坤华[3] 张儒谊[3] 佘桂源[4] 黄柳一[4] 王和平 张秋兴 王运芳[6] 李敏[6] 盛锦云[7] 官茹明 

机构地区：[1]首都儿科研究所,100020 [2]北京儿童医院 [3]重庆市儿童医院 [4]广州中山医科大学附属一院 [5]河南省平顶山哮喘病医院 [6]四川省人民医院 [7]苏州儿童医院

出　　处：《中国实用儿科杂志》2000年第10期604-606,共3页Chinese Journal of Practical Pediatrics

摘　　要：目的　进一步了解吸入皮质激素对婴幼儿哮喘的治疗作用、副作用等问题。方法　对 170例 1～ 3岁的轻中重度婴幼儿哮喘患儿 ,随机分成两组。治疗组根据病情的严重程度用面罩型筒式储雾罐吸入丙酸倍氯米松 2 5 0～ 75 0 μg/d ;对照组不用吸入激素 ,只给予酮替芬等预防性治疗。 结果　治疗组患儿发作次数、咳嗽、喘息天数均较未经吸入治疗患儿少 ,并未发现明显副作用。结论　各种严重程度的婴幼儿哮喘 ,借助面罩型储雾罐吸入皮质激素每日 2 5 0～ 75 0 μg均能收到较好疗效 ,而且安全。Objective Inhaled steroid is the first selection in treating asthma,but there was no report on the effects of it in treating infant and young asthmatic children in China .The aim of this investigation was to find the effect and side effects of inhalation beclomathasone.in treating infant and young asthmatic children.Methods 170 mild,moderate and severity patients used spacer and face mask.The control group didn't inhaled steroid.Results The frequency of asthma attack,days of cough and wheezing of asthmatic children in treating group were significantly less frequent than that in control group,and no significant side effective was found.Conclusion Treating the mild,moderate and severe infant and young asthmatic children with inhalation beclomethasone 250～750μg/day by spacer and face mask was effective and safety.

关 键 词：丙酸倍氯米松 婴幼儿哮喘 雾化吸入 

分 类 号：R725.622.5[医药卫生—儿科]