2型糖尿病肾病地区发病率及危险因素分析  

Analysis of the incidence rate and risk factors of kidney disease in type 2 diabetic nephropathy

作　　者：赵讯[1] 王学敏[1] 林海英[2] 

机构地区：[1]衡水哈励逊国际和平医院肾内科,衡水053000 [2]河北医科大学第三医院肾内科,石家庄050031

出　　处：《现代仪器》2013年第1期54-56,共3页Modern Instruments

摘　　要：目的研究本地区2型糖尿病发生糖尿病肾病(DN)发病率及相关危险因素。方法以2008-2010年在本区域就诊的1603例2型糖尿病患者中确诊为糖尿病肾病的517例患者为研究对象。根据尿微量白蛋白(UACR)将患者分为早期糖尿病肾病组(MA组)、临床糖尿病肾病组(CP组),随机选取60例糖尿病无DN患者作为糖尿病无糖尿病肾病组(NA组),对3组患者的临床资料与生化指标进行分析。结果本地区2型糖尿病患者肾脏疾病发病率为32.25%,患者组间年龄无统计学意义,CP组与MA组病程有统计学意义。MA组与CP组血压、血糖、HbA1c、LP(α)、TG水平明显高于NA组。结论病程、血压、血糖、HbA1c、LP(α)、TG是DN的危险因素。DN早期临床表现不明显,尿常规无法检测微量白蛋白尿,应对糖尿病患者定期进行有效的尿白蛋白检查。控制血压、血糖、血脂等指标是控制DN进展的关键。Abstract Objective To identify the incidence 0fkidney disease and the related risk facors on 2-type diabetic nephropathyMethods A cross-sectional study in type 2 diabetic patients were treated fi＇om 2008-2010. On the basis of UACR urinal rout and renal function. 577 2-type diabetic were divided into three groups, they were diabetic without nephropathy group（group NA） mad earlier period diabetic nephropathy （group MA） and clinical diabeticgroup（group NA） md earlier oeriod diabetic nephmpathy （group MA） and clinical diabetic nephropathy group （group CP）.The clinical data and biochemical indicator of three groups were compared .Results The prevalence of kiey disease was 32.25%. The aifference of ages has nO statistical significance. Blood pressure, glucose, HbAlc, LP （alpha）, TG levels in Group MAand group CP were Significantly higher than in NA group. COnclusion diabeti neopatyi Sct oni bid glucosi resSttr serum cholter are key points of cutting down the prevalence of diabetic nephropthy.

关 键 词：2型糖尿病 糖尿病肾病 尿微量白蛋白 危险因素 

分 类 号：R587[医药卫生—内分泌]