趋化因子与矽肺  

Chemokines and Silicosis

作　　者：肖芳[1] 高路杨[2] 王献华[1] 

机构地区：[1]河北联合大学基础医学院 [2]河北联合大学冀唐学院

出　　处：《环境卫生学杂志》2013年第1期69-71,共3页JOURNAL OF ENVIRONMENTAL HYGIENE

基　　金：河北省自然科学基金资助项目(C2008001007);河北省科学技术研究与发展计划项目(09276199D)

摘　　要：矽肺是我国发病率高,对劳动者危害严重的一类职业病。趋化因子作为一类特殊的细胞因子,在矽肺早期炎症和纤维化的发生发展中发挥重要作用。阐明趋化因子与肺纤维化发生发展的关系,更进一步了解肺纤维化的形成机制,为开辟矽肺防治新领域提供理论依据。Silicosis is a kind of occupational disease with high incidence and seriously harm to workers. Chemokines are a special class of cytokines playing an important role in the development of early inflammation and fibrosis in silicosis. Elucidating the relations of chemokines and pulmonary fibrosis development would make us to further understand the mechanism of the formation of pulmonary fibrosis and provide theoretical basis for opening up new areas of prevention and treatment of silicosis.

关 键 词：矽肺 趋化因子 肺纤维化 

分 类 号：R563.9[医药卫生—呼吸系统]