氯气作业工人健康效应及肺通气功能的研究  

Study on the health effects and pulmonary ventilatory function of workers exposed to low concentration of chlorine

作　　者：王维[1] 蒋学之[2] 任引津[3] 

机构地区：[1]安徽省职业病防治研究所,安徽合肥230022 [2]上海医科大学,上海200032 [3]上海市第六人民医院,上海200003

出　　处：《疾病控制杂志》2000年第4期330-332,共3页Chinese Journal of Disease Control and Prevention

摘　　要：目的　探讨长期接触低浓度氯气对工人健康效应及肺通气功能的影响。方法　对 376名氯气作业工人及 189名对照进行问卷调查以及内科、眼科、五官科、口腔科、心电图、胸片、肺功能检查。结果　男性接触组咳嗽、气急、角膜上皮脱落、鼻粘膜干燥、鼻粘膜苍白、心电图异常检出率显著高于对照组 ;女性接触组鼻粘膜苍白、嗅觉减退检出率高于对照组。肺功能检测表明 :女性接触组 VC%、FVC%明显降低 ,与对照组相比差异有显著性。多因素分析表明 ,除年龄、身高、吸烟指数外 ,接触指数是影响 FEV1/ FVC的重要因素。结论　长期接触低浓度氯气对工人健康产生一定影响 ,同时损害肺通气功能。Objective To investigate the potential effects on workers exposed to low concentration of chlorine. Methods An epidemiological investigation and routine physical examination, including ECG, chest X rayed and pulmonary function were performed in 367 chlorine exposers and 189 controls. Results Compared with controls, cough, short breath, cornea epithelium exfoliation, dry nasal mucosa, pale nasal mucosa, ECG abnormality in male exposers, pale nasal mucosa and hyposmia in female exposers were significantly higher. The percentage of detected value of VC, FVC was significantly decreased in female exposers. Analysis of stepwise regression indicated that FEV1/FVC were correlated with exposure parameter. Conclusions Low concentration of chlorine could seriously do harm to the workers' health and pulmonary ventilation function.

关 键 词：氯气 健康效应 肺通气功能 多因素分析 

分 类 号：R135.14[医药卫生—劳动卫生]