急性心肌梗死患者行经皮冠状动脉介入术对血清B型钠利尿肽及心室重塑的影响  

The Impact of Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention on Serum B Type Natriuretic Peptide and Ventricular Remodeling

作　　者：沈桂彬[1] 

机构地区：[1]河南省郑州市第七人民医院心内科三,450016

出　　处：《实用心脑肺血管病杂志》2013年第2期53-54,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的研究采用经皮冠状动脉介入(PCI)术对急性心肌梗死(AMI)患者血清B型钠利尿肽(BNP)及心室重塑的影响。方法将60例AMI患者按有无行PCI术分为PCI组和非PCI组,检测不同时期血清BNP水平以及采用PhillipsIE33型多普勒超声仪测定患者1周左右的左心室内径、左心室收缩末期容积(ESV)、左心室舒张末期容积(EDV)、左室射血分数(LVEF)。结果两组患者EDV、ESV和LVEF比较,差异均有统计学意义(P<0.05)。两组患者在24h、48h、72h时点血清BNP水平比较,差异均无统计学意义(P>0.05);7d时两组比较,差异有统计学意义(P<0.05)。结论采用PCI术对AMI患者进行早期再灌注可明显降低患者第7天的BNP水平,进而能改善AMI患者的左室功能及减轻左室重塑。Objective To study the impact of patients with acute myocardial infarction using percutsneous coronary intervention （PCI） for serum brain natriuretic peptide （BNP） and ventricular remodeling. Methods 60 cases of AMI patients according to the presence or absence of PCI patients will be divided into PCI group and non PCI group, serum BNP levels and detection of different periods by PhillipslE33 Doppler ultrasound determination in patients with about 1 weeks left ventrieular diameter, left ventricular end -systolic volume （ESV）, left ventricular end -diastolic volume （EDV）, left ventricular ejection fraction （LVEF）. Results In two patients with EDV, ESV and LVEF, the differences were statistically significant （P 〈0. 05）. Two patients in group 24h, 48h at 72h, serum BNP level comparison, there were no significant differences between them （P 〉 0. 05 ） ; 7d when comparing the two groups, the difference was statistically significant （P 〈 0. 05 ）. Conclusion ： With PCI early reperfusion can significantly reduce AMI patients the seventh days of the BNP concentration, and thus to improve left ventrieular function of AMI patients and reduced left ventricular remodeling in AMI patients.

关 键 词：心肌梗死 血管成形术 经腔 经皮冠状动脉 利尿肽 脑 心室重塑 

分 类 号：R542.22[医药卫生—心血管疾病]