虎杖蒽醌化合物的分离及抗氧化活性的研究  

The Separation and Antioxidant Activity Study of Anthraquinones from Polygonum Cuspidatum

作　　者：袁晓[1] 舒楚金[1] 龚二兰[1] 高俊飞[1] 袁萍[1] 

机构地区：[1]中国科学院武汉植物园,湖北武汉430074

出　　处：《食品研究与开发》2013年第2期22-24,共3页Food Research and Development

基　　金：国家科技部科技性基础性工作专项("含醌类地道中药材的测试分析标准方法及标准物质研制"编号2008FY230400)

摘　　要：利用硅胶,反相硅胶C18从中分离得到6个化合物,利用质谱、核磁共振及红外进行分析鉴定,确定其中6个蒽醌类化合物分别为大黄素-1-β-D-glu(I),大黄素-8-β-D-glu(II),大黄素甲醚-8-β-D-glu(III),2-甲氧基-6-乙酰基-7-甲基胡桃醌(IV),大黄素(V),大黄素甲醚(VI),利用DPPH法进行体外抗氧化活性的测试,发现蒽醌苷类具有一定的抗氧化活性,且BHA>I>III>II,V和VI没有活性。Six anthraquinones from roots of Polygonum Cuspidatum were separated by silica and C18 column chromatograpy. They were identified by MS, NMR, IR and UV spectra, those were identified as emodin-l-β- D-glu （I）,emodin-8-β-D-glu （II）,physcion-8-β-D-glu （III）,6-acetyl-2-methoxyl-7-methyl-juglone （IV）, emodin （V）, physcion （VI）. Their antioxidant activities were tested by DPPH assay. The results indicated that the anthraquinone glycosdes own the antioxidant activities, which are BHA〉I〉III〉II and V, VI are not activity.

关 键 词：虎杖 蒽醌类化合物 分离 抗氧化 DPPH 

分 类 号：R284[医药卫生—中药学]