抗-TP临床检测结果分析及感染趋势评估  

An Study on the Results of Clinical Testing for Anti-TP and Assessment of Its Infecting Trends

作　　者：梁勇彪[1] 杨兰[1] 覃海燕[1] 翟秀璋[1] 周元园[1] 韦永全[1] 

机构地区：[1]南宁市第二人民医院检验科,南宁530031

出　　处：《中国医药导刊》2013年第1期150-151,共2页Chinese Journal of Medicinal Guide

摘　　要：目的：了解广西地区梅毒螺旋体临床感染状况和感染趋势并作分析。方法：用酶联免疫吸附试验（ELISA）对患者进行梅毒抗体（抗-TP）检测,阳性者用梅毒螺旋体明胶颗粒凝集试验（TPPA）确认。结果：3年间共检测16 998份标本,抗-TP阳性率为3.91%,性病泌尿科的阳性率高达10.29%,且逐年大幅增长,其差异有统计学意义（χ2=24.843,P〈0.05）。女性的阳性率（4.99%）高于男性的阳性率（3.06%）,阳性患者峰值在（20~40）岁年之间。结论：近年该地区梅毒螺旋体感染趋势逐年递增,在预防,治疗及院内感染上应加大的力度。Objective：To understand the clinical infection status of Treponema pallidum in Guangxi region and analysis the infecting trends.Methods：to detect the antibodies of syphilis with enzyme-linked immunosorbent assay（ELISA） for patients,and then confirming the positives with gelatin particle agglutination（TPPA） for Treponema pallidum.Results：Positive rate of anti – TP of 16998 specimens is 3.91% in three years,while that of the dept of urological and sexually transmitted diseases is 10.29%,and a substantial increase year by year,the differences were statistically significant（χ2=24.843,P0.05）.The positive rate of female（4.99%） is higher than that of male（3.06%）,and the peak of age ranges at 20 to 40.Conclusion：Treponema pallidum infection in the region recently shows increasing trend year by year,so the prevention,treatment and nosocomial infections should be strengthen.

关 键 词：梅毒螺旋体 抗-TP 酶联免疫吸附试验(ELISA) 明胶颗粒凝集试验(TPPA) 

分 类 号：R446.6[医药卫生—诊断学]