老年人重症急性胰腺炎凝血抗凝系统变化及全身炎症反应综合症的研究  

Blood Coagulation Anticoagulation System Changes the Elderly Severe Acute Pancreatitis and Systemic Inflammatory Response Syndrome Research

作　　者：钟谷平 范惠珍 盛建文 

机构地区：[1]宜春市人民院,江西宜春336000

出　　处：《医学信息》2013年第5期65-66,共2页Journal of Medical Information

摘　　要：目的探讨凝血系统和抗凝血系统功能，在观察老年人重症急性胰腺炎病程发展变化的临床价值。方法测定血浆凝血酶原时间（PT）、部分活化凝血酶原时间（APTT）、纤维蛋白原（Fg）、D二聚体、抗凝血酶Ⅲ。结果老年人重症急性胰腺炎PT、APTT、Fg、D二聚体均高于正常对照组和轻症胰腺炎组（P〈0．05），ATⅢ低与对照组和轻症胰腺炎组（P〈0．05），全身炎症反应综合征发生比例较高（P〈0．05）。结论重症急性胰腺炎凝血系统、抗凝血系统水平和活性低下，且存在纤溶系统的亢进，发生全身炎症反应综合征的对比均有显著性意义，测定这些指标对了解病程发展和预防并发症具有一定意义．Objective To investigate the significance of coagulation system and anti-coagulation system function in elderly patients with severe acute panereatitis.Methods Determine the plasma prothrombin time （PT）, activated partial thromboplastin time （APTT）, fibrinogen （Fg）, D-dimer, antithrombin Ⅲof elderly patients with severe acute pancreatitis and the control group . Results PT, APTT, Fg, D-dimer of Elderly patients with severe acute pancreatitis were higher than the control group and the mild pancreatitis group （P〈0.05）, ATⅢ low compared with the control group and the mild pancreatitis group （P〈0.05）, systemic inflammatory response syndrome in a higher proportion （P〈0.05）. Conclusion Severe acute panereatitis coagulation system, anti-coagulation system and activity levels low, and the fibrinolytic system is in hyperthyroidism, the determination of these indicators is important to the progression and prevention of elderly patients with severe acute pancreatitis.

关 键 词：重症胰腺炎 凝血系统 抗凝血系统 全身炎症反应综合症 

分 类 号：R657.51[医药卫生—外科学]