输精管金属环节育术的可复性实验研究  

AN EXPERIMENTAL STUDY ON REVERSIBLE VAS DEFERENS OCCLUSION WITH RING-CLIPS

作　　者：周荣祥[1] 师其智[1] 郑国均[2] 张保功[1] 刘翠玉[1] 夏振开[1] 姚志伟[3] 吴照敏[2] 王友宝[1] 韩振藩[1] 

机构地区：[1]滨州医学院计划生育研究室 [2]滨州医学院病理解剖学教研室 [3]滨州医学院附属医院检验科

出　　处：《滨州医学院学报》1991年第1期22-26,95,共5页Journal of Binzhou Medical University

摘　　要：实验用健康成年家兔20只,分三个实验组和对照组。实验组施行输精管金属环节育术时,用单孔置入法分别将自制的硅胶尼龙线和马尾置入输精管腔内,术后采精化验观察6、12个月,节育效果100％。术后6个月、12个月分期取出环夹及支撑物,并分别连续采精化验观察6个月和12个月,复通率为单纯环夹组91.67％、环夹加硅胶尼龙线组100％和环夹加马尾组66.67％。连续检测血清抗精子抗体18个月,有66.11％家兔查到抗精子抗体。经光镜、电镜组织学观察发现环夹处输精管管壁结构完整,管腔存在,睾丸、附睾变化轻微,显示可复有良好的组织学基础。本研究表明手术质量、支撑物材料及环夹压力等为影响复通的因素。抗精子抗体、睾丸、输精管超微结构及细胞化学变化为影响复通后复孕的重要因素。In order to study reversible vas deferens with ring-clips, 20 rabbits were divided into four groups: (1) ring-clips with silicon-colloidal nylon line, (2) simple ring-clips, (3) ring-clips with horse-tail, (4) control group. When vas ring-clip vasoligation was performed, silicon-colloidal nylon line or horse tail was put into vas deferens lumen as a support. Sperm were examined for six, twelve months, the sterilization results were good (100％). Ring-clips and support were removed at the six, twelve months after operation. Sperm were examined for another six months, reversible rate was 100％ in group one, 91.67％ in group two and 66.67％in group three. Serum sperm antibody was detected in 66.11％ of the rabbits. Using light and electron microscopes,we found that larger structure and lumen of vas with ring-clips were intact, testis and epididymis were less changed. Histologic bases of reversing this occlusion was revealed in this study. It is suggested that surgical quality, support material and ring-clips pressure influenced the reversal of vas deferens. Sperm antibody, ultrastractral and cytichemical changes of testis and vas were the most important factors that influenced the re-fertilization following reversible vas deferens.

关 键 词：输精管 金属环节育术 可复性 

分 类 号：R699.8[医药卫生—泌尿科学]