氧预处理的BMSCs联合支架材料修复骨缺损的研究进展  

BMSCs of Oxygen Preconditioning Combining Scaffold Materials in the Reconstruction of Bone Defects

作　　者：李庆伟[1] 张聪[1] 孟纯阳[1] 

机构地区：[1]山东济宁医学院附属医院脊柱外科,山东省济宁市272029

出　　处：《组织工程与重建外科杂志》2013年第1期44-46,共3页Journal of Tissue Engineering and Reconstructive Surgery

基　　金：山东省自然科学基金(ZR2010HM090);济宁医学院青年基金(2012056)

摘　　要：骨髓间充质干细胞在一定的条件下可以分化为具有特定功能的细胞系,作为种子细胞参与骨缺损的修复,显示了良好的应用前景。氧预处理是种子细胞在种植到支架材料前,为改善细胞生存和适应能力所采取的措施,旨在减少或防止种子细胞丢失。本文就经过氧预处理的骨髓间充质干细胞联合支架材料修复骨缺损的研究进展进行综述。Bone mesenchymal stem cells （BMSC） are adult stem cells and can be differentiated into specific cell lines under certain conditions. BMSC as seed cells have showed good prospect in the reconstruction of bone defects. Oxygen Precondition with subsequent stress is carried out before planting scaffold materials to improve the cell survival and adaptation, so as to reduce or prevent the loss of seed cells. In this paper, the effects of BMSC after oxygen preconditioning combining scaffold materials in the reconstruction of bone defects were reviewed.

关 键 词：骨缺损 预处理 高压氧 支架材料 

分 类 号：Q813.12[生物学—生物工程]