糖尿病发病对健康相关生命质量状况的影响研究  

Impact of Diabetes Occurrence on Health Related Quality of Life

作　　者：王雪勇 郑卫军[2] 王晓燕[2] 

机构地区：[1]浙江省江山市贺村中心卫生院,324100 [2]浙江中医药大学基础医学院

出　　处：《中国全科医学》2013年第4期386-389,共4页Chinese General Practice

基　　金：浙江省教育厅研究项目(Y201018233);浙江中医药大学人才项目

摘　　要：目的探讨糖尿病发病对健康相关生命质量状况的影响。方法基于1136例的人群队列，采用生命质量简短量表－12（SF－12）进行生命质量状况评价，并跟踪和总结2年后糖调节受损者转归情况，应用线性回归模型探讨糖尿病发病与健康相关生命质量状况的关系。结果基线调查中未发病组与发病组的生理功能（PCS）和心理功能（MCS）得分间差异均有统计学意义（t值分别为5．4、4．2，P〈0．001）。2年后随访调查时，未发病组与发病组的PCS和Mcs得分间差异亦均有统计学意义（t值分别为10．9、8．6，P〈0．001）。随访2年内患病群体的PCS和MCS都发生了一定的变化，未发病群体基本保持不变；两组群体的PCS和MCS改变值间差异均有统计学意义（t值分别为18．5、19．4。P〈0．001）。线性回归分析得出，糖尿病发病对PCS和MCS的影响均有统计学意义（P〈0．001）。结论糖尿病发病过程中，个体生命质量水平下降明显，且2年内发病的糖调节受损者其本身生命质量状况也低于未发病者。糖尿病极大地影响了个体包括PCS和Mcs在内的健康相关生命质量状况。Objective To study the impact of diabetes occurrence on the condition of health related quality of life （HRQL） . Methods The 12 - item short - form health survey in Chinese - version （ SF - 12） was taken to assess the conditions of quality of life among 1 136 persons, and their outcome of impaired glucose regulation after two years was monitored and summarized. And then the multiple linear regression model was applied to analyze the relationship between diabetes occurrence and HRQL. Results The differences in scores of physical component summary （PCS） and mental component summary （MCS） between the occurred - disease group and the non - occurred - disease group showed statistical significance in the basic line investigation （t = 5.4, 4. 2, P 〈 0. 001 ） , and so did in the follow - up 2 years later （t = 10.9, 8.6, P 〈 0. 001 ）. During the follow - up of 2 years, both PCS and MCS had altered in the occurred - disease group, but not changed in the non - occurred - disease group, the differences of PCS and MCS between the two groups presented statistical significance （t = 18.5, 19.4, P 〈0. 001 ）. The linear regression analysis showed that the impact of both PCS and MCS had statistical significance （P 〈 0. 001 ） . Conclusion The level of an individual HRQL decreases during the occurrence of diabetes, and the HRQL of a person who has impaired glucose regulation get diabetes within 2 years is also lower than one who did not suffers the disease. The occurrence of diabetes will significantly influence the HRQL both physically and mentally.

关 键 词：糖调节受损 糖尿病 健康相关生命质量 队列研究 

分 类 号：R587.1[医药卫生—内分泌]