蛋白丢失性胃肠病诊治进展  

Progress of Diagnosis and Treatment of Protein-losing Gastroenteropathy

作　　者：董华[1] 张遵城[1] 

机构地区：[1]天津医科大学第二医院核医学科,天津300211

出　　处：《医学综述》2013年第4期661-664,共4页Medical Recapitulate

摘　　要：蛋白丢失性胃肠病(PLG)不是一个独立的原发疾病,而是继发于其他多种基础疾病的临床综合征,以水肿、腹泻、发热为主要临床表现。诊断是治疗的基础,因此不仅要确定存在蛋白质从胃肠道丢失的情况,还要明确其病因。利用放射性核素标记蛋白或其他特殊物质来检测胃肠道中的放射性,推算蛋白从胃肠道丢失的比率是PLG的特异性诊断方法之一。PLG的预后与原发病控制与否相关,因此最根本的治疗是对基础疾病的治疗,即在给予支持治疗的同时有针对性地治疗原发病,只有彻底消除引起蛋白丢失的病因,PLG才有可能得到彻底的治愈。Protein-losing gastroenteropathy（PLG） is not an independent original disease,but a seconda- ry clinical syndrome to various primary diseases with the main clinical manifestations of edema, diarrhea, and fever. The diagnosis is the foundation of treatment, therefore, not only the protein loss from the stomach and intestines should be identified, but also the explicit causes. Radioisotope-labelled human serum albumin or other special materials have been used to detect gastrointestinal protein loss rate. which is one of the specific PLG diagnosis method. PLG prognosis is correlated with the primary diseases control, consequently, most bas- ic treatment is to cure the primary diseases, i. e. specific treatment to primary disease should be given along with the support treatment. Only when the cause of protein loss is completely eliminated, can PLG be cured entirely.

关 键 词：低蛋白血症 蛋白丢失性胃肠病 肠淋巴管扩张 99Tcm-人血清白蛋白核素扫描 

分 类 号：R656.7[医药卫生—外科学]