经桡动脉行无保护左主干病变介入治疗的临床研究  

Clinical efficacy and follow up of stenting in unprotected left main coronary artery by transradial approach

作　　者：张宜春[1] 徐岩[2] 项学军[1] 宋德明[1] 

机构地区：[1]安徽医科大学附属安庆医院心血管内科,安庆246003 [2]安徽医科大学第一附属医院心血管内科,合肥230022

出　　处：《安徽医科大学学报》2013年第4期428-431,共4页Acta Universitatis Medicinalis Anhui

基　　金：安徽省科技攻关项目(编号:09010302083);安徽省卫生厅医学科研重点项目(编号:2010B005)

摘　　要：56例经桡动脉路径行无保护左冠状动脉主干(ULM-CA)病变患者分为分叉组(n=36)和非分叉组(n=20),分叉组和非分叉组的临床基线情况差异无统计学意义。根据Syntax积分分为低危组(n=42)和高危组(n=14),Syntax评分与心率震荡、血浆脑钠肽、左室射血分数有良好的相关性。根据病变特点行单支架术或双支架术,住院期间无主要不良心脏事件(MACE)发生,平均随访(11.25±4.72)个月,MACE发生8例(14.29%)。经桡动脉行ULMCA病变介入治疗是安全有效的,且近远期预后良好。A total of 56 unprotected left main coronary artery （ULMCA） patients treated by transradial approach were classified into bifurcation group （ n = 36 ） and non-bifurcation group （ n = 20 ）. Most of the clinical baseline conditions were similar between both groups. Patients were classified into mild group （n = 42） and severe group （n = 14）according to Syntax score. Significant correlations were found between Syntax score and the left ventricular e- jection fraction（LVEF） as well as with heart rate turbulence（HRT）. Both groups received single stenting or double stenting according to the lesions characteristics. No major adverse cardiac event （MACE） occurred in hospital. 56 patients had followed up with a duration of （ 11.25 ＋ 4.72） months, during which MACE developed in 8 cases （ 14.29% ）. Stenting in ULMCA by transradial approach proves safe and feasible, with good short and long - term outcomes.

关 键 词：无保护左冠状动脉主干 经皮冠状动脉介入治疗 主要不良心脏事件 SYNTAX评分 

分 类 号：R543[医药卫生—心血管疾病]